# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4371947 | Binding | Inhibition of human transmembrane domain deficient FFAH expressed in Escherichia coli using AAMCA as substrate incubated for 1 min measured for 50 mins by fluorescence assay | Homo sapiens | 27 | ALA4371025 | assay format | Scientific Literature | |
2. | ALA4371948 | Binding | Inhibition of rat FFAH expressed in Escherichia coli using AAMCA as substrate incubated for 1 min measured for 50 mins by fluorescence assay | Rattus norvegicus | 24 | ALA4371025 | assay format | Scientific Literature | |
3. | ALA4371950 | ADME | Intrinsic metabolic stability in human liver microsomes assessed as metabolic turnover rate per mg protein at 1 uM preincubated for 5 mins followed by NADPH cofactor addition and measured after 30 mins by LC-MS/MS analysis | Homo sapiens | 15 | ALA4371025 | microsome format | Scientific Literature | |
4. | ALA4371951 | ADME | Intrinsic metabolic stability in rat liver microsomes assessed as metabolic turnover over per mg protein at 1 uM preincubated for 5 mins followed by NADPH cofactor addition and measured after 30 mins by LC-MS/MS analysis | Rattus norvegicus | 15 | ALA4371025 | microsome format | Scientific Literature |