| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4378467 | B | Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarization | Homo sapiens | 6 | ALA4376822 | single protein format | Scientific Literature | |
| 2. | ALA5096341 | B | Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and biotinylated Bim BH3 peptide interaction using Biotin-DMRPEIWIAQELRRIGDEFNAYYARR as substrate incubated for 60 mins by TR-FRET analysis | Homo sapiens | 12 | ALA5096144 | assay format | Scientific Literature | |
| 3. | ALA5096342 | F | Anticancer activity against human OPM-2 cells assessed as inhibition of cell viability incubated for 24 hrs in presence of 10% FBS by Cell-titer Glo assay | Homo sapiens | 12 | ALA5096144 | cell-based format | Scientific Literature | |
| 4. | ALA5242715 | B | Binding affinity to Mcl-1 (unknown origin) | Homo sapiens | 3 | ALA5241100 | single protein format | Scientific Literature | |
| 5. | ALA5242716 | A | Oral bioavailability in mouse | Mus musculus | 2 | ALA5241100 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!