#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4430346	B	Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs by luciferase reporter gene based mammalian two-hybrid assay	Homo sapiens	13		cell-based format	Scientific Literature
2.	ALA4430348	B	Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity at 100 nM incubated for 24 hrs by luciferase reporter gene based mammalian two-hybrid assay relative to bexarotene	Homo sapiens	12		cell-based format	Scientific Literature
3.	ALA4430352	B	Agonist activity at human RXRalpha expressed in human HCT116 cells assessed as increase in RXRE-mediated transcription at 25 nM incubated for 24 hrs by RXRE luciferase reporter gene assay relative to bexarotene	Homo sapiens	7		cell-based format	Scientific Literature
4.	ALA4430353	B	Agonist activity at human RXRalpha expressed in human HCT116 cells assessed as increase in RXRE-mediated transcription at 100 nM incubated for 24 hrs by RXRE luciferase reporter gene assay relative to bexarotene	Homo sapiens	8		cell-based format	Scientific Literature
5.	ALA4430354	B	Agonist activity at human RXRalpha expressed in human HCT116 cells assessed as increase in RXRE-mediated transcription at 1000 nM incubated for 24 hrs by RXRE luciferase reporter gene assay relative to bexarotene	Homo sapiens	10		cell-based format	Scientific Literature
6.	ALA4430356	B	Selectivity index, ratio of agonist activity at human RARalpha expressed in HEK293 cells assessed as increase in RARE-mediated transcription relative to bexarotene to agonist activity at human RXRalpha expressed in human HCT116 cells assessed as increase in RXRE-mediated transcription relative to bexarotene	Homo sapiens	8		cell-based format	Scientific Literature
7.	ALA4430357	A	Agonist activity at human RXRalpha/LXRalpha expressed in human HCT116 cells assessed as reduction in SREBP-mediated transcription activity at 100 nM incubated for 24 hrs by luciferase reporter gene assay relative to bexarotene	Homo sapiens	12		cell-based format	Scientific Literature
8.	ALA4430358	A	Agonist activity at human RXRalpha/LXRalpha expressed in human HCT116 cells assessed as reduction in SREBP-mediated transcription activity at 100 nM incubated for 24 hrs by luciferase reporter gene assay in presence of 100 nM LXR agonist TO901317 relative to bexarotene	Homo sapiens	8		cell-based format	Scientific Literature
9.	ALA4430359	U	Lipid risk index, ratio of agonist activity at human RXRalpha/LXRalpha expressed in human HCT116 cells assessed as reduction in SREBP-mediated transcription activity to agonist activity at human RXRalpha expressed in human HCT116 cells assessed as increase in RXRE-mediated transcription	Homo sapiens	8		cell-based format	Scientific Literature
10.	ALA4430360	B	Agonist activity at RXR in human HepG2 cells assessed as induction of CYP3A4 expression at 100 nM incubated for 24 hrs by quantitative real-time PCR method relative to untreated control	Homo sapiens	11		cell-based format	Scientific Literature
11.	ALA4430361	F	Growth inhibition of human HUT78 cells at 200 nM incubated for 72 hrs by MTS assay relative to bexarotene	Homo sapiens	10		cell-based format	Scientific Literature
12.	ALA4430363	T	Mutagenicity in Saccharomyces cerevisiae D7 assessed as induction of mutagenesis by measuring forward and reverse mutations up to 0.1 mg/mL	Saccharomyces cerevisiae	13		assay format	Scientific Literature