| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4364068 | Binding | Inhibition of human recombinant MBP-tagged FAAH expressed in Escherichia coli cells using AAMCA as substrate incubated for 15 mins followed by substrate addition and measured after every 20 mins for 4 hrs by fluorescence based assay | Homo sapiens | 33 | ALA4359929 | cell-based format | Scientific Literature | |
| 2. | ALA4364069 | Binding | Inhibition of rat recombinant His/GST-tagged FAAH expressed in Escherichia coli cells using AAMCA as substrate incubated for 15 mins followed by substrate addition and measured after every 20 mins for 4 hrs by fluorescence based assay | Rattus norvegicus | 32 | ALA4359929 | cell-based format | Scientific Literature | |
| 3. | ALA4364070 | Binding | Inhibition of human recombinant His-tagged MGL expressed in Escherichia coli BL21 DE3 cells using AHMMCE as substrate preincubated with enzyme for 15 mins followed by substrate addition and measured after every 15 mins for 3 hrs by fluorescence based assay | Homo sapiens | 38 | ALA4359929 | cell-based format | Scientific Literature | |
| 4. | ALA4364080 | ADME | Stability in human liver microsomes assessed as half life | Homo sapiens | 21 | ALA4359929 | microsome format | Scientific Literature | |
| 5. | ALA4364081 | ADME | Stability in rat liver microsomes assessed as half life | Rattus norvegicus | 21 | ALA4359929 | microsome format | Scientific Literature | |
| 6. | ALA4364082 | ADME | Stability in mouse liver microsomes assessed as half life | Mus musculus | 21 | ALA4359929 | microsome format | Scientific Literature | |
| 7. | ALA4364083 | ADME | Stability in human plasma assessed as half life | Homo sapiens | 21 | ALA4359929 | cell-free format | Scientific Literature | |
| 8. | ALA4364084 | ADME | Stability in rat plasma assessed as half life | Rattus norvegicus | 21 | ALA4359929 | cell-free format | Scientific Literature | |
| 9. | ALA4364085 | ADME | Stability in mouse plasma assessed as half life | Mus musculus | 21 | ALA4359929 | cell-free format | Scientific Literature | |
| 10. | ALA4364086 | ADME | Stability in human gastric fluid assessed as half life | Homo sapiens | 21 | ALA4359929 | tissue-based format | Scientific Literature | |
| 11. | ALA4364087 | ADME | Stability in rat gastric fluid assessed as half life | Rattus norvegicus | 21 | ALA4359929 | tissue-based format | Scientific Literature | |
| 12. | ALA4364088 | ADME | Stability in mouse gastric fluid assessed as half life | Mus musculus | 21 | ALA4359929 | tissue-based format | Scientific Literature | |
| 13. | ALA4364095 | Binding | Selectivity ratio of IC50 for human recombinant His-tagged MGL expressed in Escherichia coli BL21 DE3 cells to IC50 for human recombinant MBP-tagged FAAH expressed in Escherichia coli cells by fluorescence based assay | Homo sapiens | 34 | ALA4359929 | cell-based format | Scientific Literature | |
| 14. | ALA4364096 | Binding | Selectivity ratio of IC50 for human full length ABHD6 expressed in Escherichia coli cells to IC50 for human recombinant MBP-tagged FAAH expressed in Escherichia coli cells by fluorescence based assay | Homo sapiens | 34 | ALA4359929 | cell-based format | Scientific Literature | |
| 15. | ALA4364097 | Binding | Displacement of [3H]CP55940 from CB1 receptor in rat brain by competition-equilibrium binding analysis | Rattus norvegicus | 40 | ALA4359929 | tissue-based format | Scientific Literature | |
| 16. | ALA4364098 | Binding | Displacement of [3H]CP55940 from CB2 receptor in rat brain by competition-equilibrium binding analysis | Rattus norvegicus | 40 | ALA4359929 | tissue-based format | Scientific Literature | |
| 17. | ALA4364099 | Binding | Displacement of [3H]CP55940 from mouse CB2 receptor expressed in HEK293 cells by competition-equilibrium binding analysis | Mus musculus | 40 | ALA4359929 | cell-based format | Scientific Literature | |
| 18. | ALA4364100 | Binding | Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells by competition-equilibrium binding analysis | Homo sapiens | 40 | ALA4359929 | cell-based format | Scientific Literature | |
| 19. | ALA4364103 | Binding | Selectivity ratio of IC50 for human recombinant His-tagged MGL expressed in Escherichia coli BL21 DE3 cells to IC50 for rat recombinant His/GST-tagged FAAH expressed in Escherichia coli cells by fluorescence based assay | 34 | ALA4359929 | cell-based format | Scientific Literature | ||
| 20. | ALA4364104 | Binding | Selectivity ratio of IC50 for human full length ABHD6 expressed in Escherichia coli cells to IC50 for rat recombinant His/GST-tagged FAAH expressed in Escherichia coli cells by fluorescence based assay | 34 | ALA4359929 | cell-based format | Scientific Literature |
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