| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4409524 | B | Inhibition of recombinant human N-terminal GST-tagged Bcl-xl (1 to 209 residues) expressed in Escherichia coli using HyLite Fluor 647-labeled BIM peptide as substrate incubated for 120 to 180 mins by TR-FRET assay | Homo sapiens | 12 | ALA4406861 | assay format | Scientific Literature | |
| 2. | ALA4409525 | B | Inhibition of recombinant human C-terminal 6xHis-tagged Bcl-2 (M1 to F212 residues) expressed in Escherichia coli using HyLite Fluor 647-labeled BIM peptide as substrate incubated for 120 to 180 mins by TR-FRET assay | Homo sapiens | 12 | ALA4406861 | assay format | Scientific Literature | |
| 3. | ALA4409526 | B | Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide as substrate incubated for 120 to 180 mins by TR-FRET assay | Homo sapiens | 12 | ALA4406861 | assay format | Scientific Literature | |
| 4. | ALA4409527 | B | Inhibition of recombinant human C-terminal 6xHis-tagged Mcl-1 (E171 ti G327) expressed in Escherichia coli using biotin-labeled BIM peptide as substrate incubated for 120 to 180 mins by TR-FRET assay | Homo sapiens | 12 | ALA4406861 | assay format | Scientific Literature | |
| 5. | ALA4409528 | B | Inhibition of Bcl-xl in human U266B1 cells assessed as caspase 3/7 activation for 6 hrs by Caspase 3/7-Glo luminescence assay | Homo sapiens | 12 | ALA4406861 | cell-based format | Scientific Literature | |
| 6. | ALA4409529 | B | Inhibition of Bcl-xl in human U266B1 cells assessed as caspase 3/7 activation in presence of 10 % serum for 6 hrs by Caspase 3/7-Glo luminescence assay | Homo sapiens | 12 | ALA4406861 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!