# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4433043 | Binding | Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by TR-FRET assay | Homo sapiens | 38 | ALA4431389 | assay format | Scientific Literature | |
2. | ALA4433044 | Binding | Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluorescence polarization assay | Homo sapiens | 38 | ALA4431389 | assay format | Scientific Literature | |
3. | ALA4433045 | Binding | Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM addition measured after 3.5 hrs by flow cytometric analysis | Homo sapiens | 38 | ALA4431389 | cell-based format | Scientific Literature | |
4. | ALA4433046 | Binding | Inhibition of human ERG expressed in CHOK1 cell membranes after 2 hrs by cy3b-dofetilide-based fluorescence polarization assay | Homo sapiens | 38 | ALA4431389 | cell-based format | Scientific Literature | |
5. | ALA4433051 | ADME | Binding affinity to human serum albumin by HPLC analysis | Homo sapiens | 30 | ALA4431389 | single protein format | Scientific Literature | |
6. | ALA4433073 | Physicochemical | Lipophilicity, log D of the compound by chromatographic method | 30 | ALA4431389 | small-molecule physicochemical format | Scientific Literature |