# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4365224 | ADME | Hemolytic activity in human RBC assessed as hemolysis at 320 to 640 uM measured after 1 hr | Homo sapiens | 12 | ALA4364261 | cell-based format | Scientific Literature | |
2. | ALA4365225 | ADME | Hemolytic activity in human RBC assessed as hemolysis at 40 uM measured after 1 hr | Homo sapiens | 12 | ALA4364261 | cell-based format | Scientific Literature | |
3. | ALA4365226 | ADME | Stability of the compound assessed as Engyodontium album PMSF-pretreated proteinase K-mediated compound hydrolysis at 20 uM incubated for 10 mins at 70 degC by coomassie blue staining-based NuPAGE analysis | Engyodontium album | 6 | ALA4364261 | assay format | Scientific Literature | |
4. | ALA4365231 | Functional | Antibacterial activity against Escherichia coli K-12 measured after 20 hrs by microtiter dilution method | Escherichia coli | 12 | ALA4364261 | organism-based format | Scientific Literature | |
5. | ALA4365232 | Functional | Antibacterial activity against Pseudomonas aeruginosa PAO1 measured after 20 hrs by microtiter dilution method | Pseudomonas aeruginosa | 12 | ALA4364261 | organism-based format | Scientific Literature | |
6. | ALA4365233 | Functional | Antibacterial activity against tobramycin-pretreated Pseudomonas aeruginosa isolate 214 measured after 20 hrs by microtiter dilution method | Pseudomonas aeruginosa | 12 | ALA4364261 | organism-based format | Scientific Literature | |
7. | ALA4365234 | Functional | Antibacterial activity against tobramycin-pretreated Pseudomonas aeruginosa isolate 287 measured after 20 hrs by microtiter dilution method | Pseudomonas aeruginosa | 12 | ALA4364261 | organism-based format | Scientific Literature | |
8. | ALA4365235 | Functional | Antibacterial activity against tobramycin-pretreated Pseudomonas aeruginosa isolate 330 after 20 hrs by microtiter dilution method | Pseudomonas aeruginosa | 12 | ALA4364261 | organism-based format | Scientific Literature | |
9. | ALA4365236 | Functional | Antibacterial activity against tobramycin-pretreated Pseudomonas aeruginosa isolate 380 after 20 hrs by microtiter dilution method | Pseudomonas aeruginosa | 12 | ALA4364261 | organism-based format | Scientific Literature | |
10. | ALA4365237 | Binding | Binding affinity to Escherichia coli lipid extract liposome membrane at 25 uM by CD spectroscopic analysis | Escherichia coli | 12 | ALA4364261 | cell membrane format | Scientific Literature | |
11. | ALA4365238 | Binding | Binding affinity to Escherichia coli lipid extract liposome membrane at 10 uM by tryptophan fluorescence method | Escherichia coli | 6 | ALA4364261 | cell membrane format | Scientific Literature | |
12. | ALA4365239 | ADME | Binding affinity to POPC membrane at 25 uM by CD spectroscopic analysis | 12 | ALA4364261 | assay format | Scientific Literature | ||
13. | ALA4365243 | Binding | Induction of terbium(3)-loaded Escherichia coli lipid extract liposome membrane disruption at 10 uM measured after 20 mins by fluorescence assay relative to control | Escherichia coli | 12 | ALA4364261 | cell membrane format | Scientific Literature |