| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4395512 | B | Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 mins by malachite green dye based pyrophosphatase coupled colorimetric assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA4395513 | B | Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells by isothermal titration calorimetry | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4395514 | B | Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isothermal titration calorimetry | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 4. | ALA4395515 | B | Inhibition of BACE1 (unknown origin) using HiLyte Fluo488/QXL-520 as substrate by FRET assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA4395517 | B | Stabilization of MTH1 in human K562 cells assessed as unprecipitated protein expression at 0.15 to 20 uM incubated for 60 mins at elevated melting temperature by CESTA based western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4395518 | F | Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by resazurin dye based fluorescent assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4395519 | B | Inhibition of BACE1 (unknown origin) at 200 uM using HiLyte Fluo488/QXL-520 as substrate by FRET assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA4395520 | B | Inhibition of fluorescently labeled tracer binding to human ERG at 200 uM by competitive binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4395521 | B | Selectivity ratio of IC50 for BACE1 (unknown origin) to IC50 for recombinant His-tagged MLTH1 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA4395522 | B | Selectivity ratio for recombinant His-tagged MLTH1 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells over human ERG | Homo sapiens | 1 | cell-based format | Scientific Literature |
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