#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4402146	Binding	Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by HTRF assay	Homo sapiens	32	ALA4400567	assay format	Scientific Literature
2.	ALA4402147	Functional	Antiproliferative activity against human HEL cells harboring JAK2 V617F mutant measured after 48 hrs by CellTiter-Glo assay	Homo sapiens	9	ALA4400567	cell-based format	Scientific Literature
3.	ALA4402148	ADME	Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by HTRF assay	Homo sapiens	32	ALA4400567	assay format	Scientific Literature
4.	ALA4402149	ADME	Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by HTRF assay	Homo sapiens	32	ALA4400567	assay format	Scientific Literature
5.	ALA4402150	Binding	Selectivity ratio of IC50 for recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system to IC50 for recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system	Homo sapiens	8	ALA4400567	assay format	Scientific Literature
6.	ALA4402151	Binding	Selectivity ratio of IC50 for recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system to IC50 for recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system	Homo sapiens	15	ALA4400567	assay format	Scientific Literature
7.	ALA4402153	ADME	Cytotoxicity against IL-4 induced JAK1/3 activated human THP1 cells preincubated for 1 hr followed by IL-4 induction and measured after 1 hr by CellTiter-Glo assay	Homo sapiens	9	ALA4400567	cell-based format	Scientific Literature
8.	ALA4402154	ADME	Cytotoxicity against human NK92 cells harboring JAK1/3 measured after 48 hrs by CellTiter-Glo assay	Homo sapiens	9	ALA4400567	cell-based format	Scientific Literature
9.	ALA4402155	Binding	Inhibition of JAK2 in Lewis rat T cells assessed as reduction in IL-2-induced cell proliferation measured after 72 hrs by alamar blue staining based fluorescence assay	Rattus norvegicus	9	ALA4400567	cell-based format	Scientific Literature
10.	ALA4402156	Binding	Inhibition of JAK2 in Lewis rat T cells assessed as reduction in ConA/CD3/CD28-induced cell proliferation measured after 72 hrs by alamar blue staining based fluorescence assay	Rattus norvegicus	9	ALA4400567	cell-based format	Scientific Literature
11.	ALA4402159	Functional	Antiproliferative activity against JAK2 wild-type human TF1 cells measured after 48 hrs by CellTiter-Glo assay	Homo sapiens	9	ALA4400567	cell-based format	Scientific Literature
12.	ALA4402160	Binding	Inhibition of JAK2 in human TF1 cells assessed as reduction in GM-CSF-induced STAT5 phosphorylation at 10 uM preincubated for 1 hr followed by GM-CSF stimulation and measured after 20 mins by Western blot analysis	Homo sapiens	6	ALA4400567	cell-based format	Scientific Literature