| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4362335 | B | Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's method | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 2. | ALA4362336 | B | Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's method | Rattus norvegicus | 14 | single protein format | Scientific Literature | ||
| 3. | ALA4362337 | B | Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colorimetry | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 4. | ALA4362338 | B | Reversible inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins in presence of NADPH followed by substrate addition and measured for 20 mins by Ellman's method | Rattus norvegicus | 6 | single protein format | Scientific Literature | ||
| 5. | ALA4362339 | F | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA4362340 | F | Cytotoxicity against human U87 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA4362341 | A | Cytotoxicity against human PBMC assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA4362342 | A | Cytotoxicity against human HaCaT assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4362343 | F | Induction of ROS generation in human SH-SY5Y cells incubated for 24 hrs by DHE staining based flow cytometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA4362344 | F | Induction of ROS generation in human U87 cells incubated for 24 hrs by DHE staining based flow cytometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA4362345 | A | Induction of ROS generation in human HaCaT cells incubated for 24 hrs by DHE staining based flow cytometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA4362346 | F | Induction of RNS generation in human SH-SY5Y cells incubated for 24 hrs by DHR staining based flow cytometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 13. | ALA4362347 | F | Induction of RNS generation in human U87 cells incubated for 24 hrs by DHR staining based flow cytometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 14. | ALA4362348 | A | Induction of RNS generation in human HaCaT cells incubated for 24 hrs by DHR staining based flow cytometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 15. | ALA4362349 | F | Induction of apoptosis in human SH-SY5Y cells assessed as viable cells incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry (Rvb = 92.44 %) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 16. | ALA4362350 | F | Induction of apoptosis in human SH-SY5Y cells assessed as early apoptotic cells incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry (Rvb = 0.44 %) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 17. | ALA4362351 | F | Induction of apoptosis in human SH-SY5Y cells assessed as late apoptotic cells incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry (Rvb = 1.37 %) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA4362352 | F | Induction of apoptosis in human SH-SY5Y cells assessed as necrotic cells incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry (Rvb = 5.75 %) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 19. | ALA4362353 | A | Induction of apoptosis in human HaCaT cells assessed as viable cells incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry (Rvb = 95.78 %) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 20. | ALA4362354 | A | Induction of apoptosis in human HaCaT cells assessed as early apoptotic cells incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry (Rvb = 0.02 %) | Homo sapiens | 6 | cell-based format | Scientific Literature |
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