# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4374632 | F | Antiproliferative activity against human MEC1 cells assessed as reduction in cell viability by alamar blue assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
2. | ALA4374633 | P | Half life in aqueous solution at pH 7.4 | 10 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA4374634 | A | Intrinsic clearance in mouse hepatocytes assessed as per million cells | Mus musculus | 10 | cell-based format | Scientific Literature | ||
4. | ALA4374635 | A | Half life in mouse hepatocytes | Mus musculus | 10 | cell-based format | Scientific Literature | ||
5. | ALA4374636 | A | Permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
6. | ALA4374637 | A | Permeability across basolateral to apical side in human Caco2 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
7. | ALA4374638 | A | Efflux ratio of permeability from basolateral to apical side over apical to basolateral side in human Caco2 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
8. | ALA4374639 | A | Intrinsic clearance in mouse liver microsomes | Mus musculus | 7 | microsome format | Scientific Literature | ||
9. | ALA4374640 | A | Intrinsic clearance in mouse at 1 mg/kg ,iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
10. | ALA4374641 | A | Half life in mouse at 1 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
11. | ALA4374642 | A | Volume of distribution at steady state in mouse at 1 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
12. | ALA4374643 | A | AUC (0 to infinity) in mouse at 1 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
13. | ALA4374644 | A | Tmax in mouse at 10 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
14. | ALA4374645 | A | Cmax in mouse at 10 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA4374646 | A | Oral bioavailability in mouse at 10 mg/kg | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA4374647 | A | AUC in mouse at 10 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
17. | ALA4374648 | F | Antiproliferative activity against human MEC1 cells assessed as cell death in presence of ROS scavenger N-acetyl-L-cysteine by alamar blue assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4374649 | B | Inhibition of full length human ERG expressed in Chinese hamster ovary cells at -70 mV holding potential by patch clamp method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
19. | ALA4374650 | B | Inhibition of full length human ERG expressed in Chinese hamster ovary cells at 100 uM at -70 mV holding potential by patch clamp method relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature |