| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4412538 | B | Binding affinity to AGPS (unknown origin) assessed as change in melting temperature at 180 uM by ThermoFAD assay | Homo sapiens | 23 | ALA4411293 | single protein format | Scientific Literature | |
| 2. | ALA4412539 | B | Inhibition of AGPS (unknown origin) using palmitoyl-DHAP as substrate in presence of [1-14C]hexadecanol by radioactivity based enzymatic assay | Homo sapiens | 5 | ALA4411293 | single protein format | Scientific Literature | |
| 3. | ALA4412540 | F | Down regulation of phospholipids in human 231MFP cells at 500 uM after 24 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 4. | ALA4412541 | F | Antimigratory activity in human 231MFP cells at 500 uM after 6 hrs by transwell assay relative to control | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 5. | ALA4412543 | A | Cytotoxicity against human 231MFP cells assessed as cell survival at 500 uM after 24 hrs by MTS assay relative to control | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 6. | ALA4412544 | A | Cytotoxicity against human 231MFP cells assessed as cell survival at 500 uM after 48 hrs by MTS assay relative to control | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 7. | ALA4412545 | F | Antiproliferative activity against human PC3 cells at 100 uM after 24 hrs by MTS assay | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 8. | ALA4412546 | F | Antiproliferative activity against human MDA-MB-231 cells at 100 uM after 24 hrs by MTS assay | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 9. | ALA4412547 | A | Cytotoxicity against human MeT-5A cells at 100 uM after 24 hrs by MTS assay | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 10. | ALA4412548 | F | Antiproliferative activity against human PC3 cells at 250 uM after 24 hrs by MTS assay | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 11. | ALA4412549 | F | Antiproliferative activity against human MDA-MB-231 cells at 250 uM after 24 hrs by MTS assay | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 12. | ALA4412550 | F | Modulation of epithelial-mesenchymal transition in human PC3 cells assessed as upregulation of E-cadherin mRNA expression at 50 to 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 3 | ALA4411293 | cell-based format | Scientific Literature | |
| 13. | ALA4412551 | F | Modulation of epithelial-mesenchymal transition in human MDA-MB-231 cells assessed as upregulation of E-cadherin mRNA expression at 50 to 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 3 | ALA4411293 | cell-based format | Scientific Literature | |
| 14. | ALA4412552 | F | Modulation of epithelial-mesenchymal transition in human PC3 cells assessed as down regulation of snail mRNA expression at 50 to 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 3 | ALA4411293 | cell-based format | Scientific Literature | |
| 15. | ALA4412553 | F | Modulation of epithelial-mesenchymal transition in human MDA-MB-231 cells assessed as down regulation of snail mRNA expression at 50 to 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 3 | ALA4411293 | cell-based format | Scientific Literature | |
| 16. | ALA4412554 | F | Modulation of epithelial-mesenchymal transition in human PC3 cells assessed as down regulation of MMP2 mRNA expression at 50 to 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 3 | ALA4411293 | cell-based format | Scientific Literature | |
| 17. | ALA4412555 | F | Modulation of epithelial-mesenchymal transition in human MDA-MB-231 cells assessed as down regulation of MMP2 mRNA expression at 50 to 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 3 | ALA4411293 | cell-based format | Scientific Literature | |
| 18. | ALA4412556 | F | Modulation of epithelial-mesenchymal transition in human MDA-MB-231 cells transfected with AGPS-siRNA assessed as upregulation of E-cadherin mRNA expression at 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 19. | ALA4412557 | F | Modulation of epithelial-mesenchymal transition in human MDA-MB-231 cells transfected with AGPS-siRNA assessed as down regulation of snail mRNA expression at 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature | |
| 20. | ALA4412558 | F | Modulation of epithelial-mesenchymal transition in human MDA-MB-231 cells transfected with AGPS-siRNA assessed as down regulation of MMP2 mRNA expression at 100 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA4411293 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!