| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4393787 | P | Octanol-phosphate buffer partition co-efficient, log D of the compound at pH 7.4 after 2 hrs by LC-MS/MS-based shake flask method | 12 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA4393788 | P | Aqueous solubility of the compound in pH 7.4 phosphate buffer measured after 24 hrs by LC-MS/MS-based shake flask method | 12 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4393789 | B | Inhibition of [3H]MK0591 binding to human FLAP expressed in human COS7 cell membranes measured after 60 to 80 mins by microbeta scintillation counting method | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 4. | ALA4393790 | B | Inhibition of FLAP in human whole blood assessed as reduction in calcium ionophore-stimulated LTB4 production preincubated for 4 hrs followed by calcium ionophore stimulation and measured after 20 mins by EIA | Homo sapiens | 12 | tissue-based format | Scientific Literature | ||
| 5. | ALA4393791 | A | Intrinsic clearance in human hepatocytes assessed per million cells at 1 uM measured after 2 to 60 mins by LC-MS/MS analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 6. | ALA4393792 | A | Intrinsic clearance in rat hepatocytes assessed per million cells at 1 uM measured after 2 to 60 mins by LC-MS/MS analysis | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
| 7. | ALA4393793 | A | Passive apparent permeability across apical to basolateral side in human Caco2 cells at pH 6.5 | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 8. | ALA4393794 | T | Mutagenicity in Salmonella typhimurium TA98 in presence of rat S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 12 | subcellular format | Scientific Literature | ||
| 9. | ALA4393795 | T | Mutagenicity in Salmonella typhimurium TA98 in absence of rat S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 12 | assay format | Scientific Literature | ||
| 10. | ALA4393796 | T | Mutagenicity in Salmonella typhimurium TA100 in presence of rat S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 12 | subcellular format | Scientific Literature | ||
| 11. | ALA4393797 | T | Mutagenicity in Salmonella typhimurium TA100 in absence of rat S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 12 | assay format | Scientific Literature | ||
| 12. | ALA4393798 | A | Inhibition of recombinant human CYP2C8 expressed in Escherichia coli using luciferin-ME as substrate by fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 13. | ALA4393799 | A | Inhibition of recombinant human CYP1A2 expressed in Escherichia coli using CEC as substrate by fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 14. | ALA4393800 | A | Inhibition of recombinant human CYP2C9 expressed in Escherichia coli using 7MFC as substrate by fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 15. | ALA4393801 | A | Inhibition of recombinant human CYP2C19 expressed in Escherichia coli using CEC as substrate by fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 16. | ALA4393802 | A | Inhibition of recombinant human CYP2D6 expressed in Escherichia coli using MAMC as substrate by fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 17. | ALA4393803 | A | Inhibition of recombinant human CYP3A4 expressed in Escherichia coli using BFC as substrate by fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 18. | ALA4393804 | A | Glutathione reactivity in human liver microsomes assessed as adduct formation by QTOF-MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 19. | ALA4393805 | A | Drug metabolism in human liver microsomes assessed as cyanide-compound adduct formation by QTOF-MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 20. | ALA4393806 | A | Drug metabolism in human liver microsomes assessed as methoxylamine-compound adduct formation by QTOF-MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature |
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