# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4344346 | Binding | Inhibition of DYRK1A (unknown origin) at 1000 nM by FRET-based Lantha-screen Eu kinase binding assay relative to control | Homo sapiens | 24 | ALA4342463 | single protein format | Scientific Literature | |
2. | ALA4344347 | Binding | Inhibition of DYRK1A (unknown origin) at 300 nM by FRET-based Lantha-screen Eu kinase binding assay relative to control | Homo sapiens | 24 | ALA4342463 | single protein format | Scientific Literature | |
3. | ALA4344348 | Binding | Inhibition of DYRK1A (unknown origin) by FRET-based Lantha-screen Eu kinase binding assay | Homo sapiens | 21 | ALA4342463 | single protein format | Scientific Literature | |
4. | ALA4344349 | Functional | Induction of beta-cell proliferation in human pancreatic islets at 10 uM incubated for 96 hrs by Ki67-insulin co-immunolabeling assay | Homo sapiens | 6 | ALA4342463 | cell-based format | Scientific Literature | |
5. | ALA4344350 | Functional | Induction of beta-cell proliferation in human pancreatic islets incubated for 96 hrs by Ki67-insulin co-immunolabeling assay | Homo sapiens | 5 | ALA4342463 | cell-based format | Scientific Literature | |
6. | ALA4344352 | Binding | Inhibition of DYRK1A in mouse R7T1 cells expressing expressing NFAT2-GFP assessed as induction of NFAT2- GFP nuclear translocation at 10 uM incubated for 24 hrs | Mus musculus | 6 | ALA4342463 | cell-based format | Scientific Literature |