# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4434268 | B | Agonist activity at human Kv7.2/Kv7.3 expressed in HEK293 cells assessed as drug concentration that doubles the conductance at voltage leading to 15% channel activation at holding potential of at -80 mV by whole cell patch clamp electrophysiology assay | Homo sapiens | 22 | ALA4433246 | cell-based format | Scientific Literature | |
2. | ALA4434269 | B | Agonist activity at human Kv7.3/Kv7.5 expressed in HEK293 cells assessed as drug concentration that doubles the conductance at voltage leading to 15% channel activation at holding potential of at -80 mV by whole cell patch clamp electrophysiology assay | Homo sapiens | 22 | ALA4433246 | cell-based format | Scientific Literature | |
3. | ALA4434270 | B | Agonist activity at human Kv7.4 expressed in HEK293 cells assessed as drug concentration that doubles the conductance at voltage leading to 15% channel activation at holding potential of at -80 mV by whole cell patch clamp electrophysiology assay | Homo sapiens | 22 | ALA4433246 | cell-based format | Scientific Literature | |
4. | ALA4434271 | B | Agonist activity at human Kv7.4/Kv7.5 expressed in HEK293 cells assessed as drug concentration that doubles the conductance at voltage leading to 15% channel activation at holding potential of at -80 mV by whole cell patch clamp electrophysiology assay | Homo sapiens | 22 | ALA4433246 | cell-based format | Scientific Literature | |
5. | ALA4434272 | B | Selectivity index, ratio of EC2x for human Kv7.4/5 expressed in HEK293 cells to EC2x for EC2x for human Kv7.2/3 expressed in HEK293 cells | Homo sapiens | 22 | ALA4433246 | cell-based format | Scientific Literature |