# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4373923 | F | Antiparasitic activity against Nippostrongylus brasiliensis L4 assessed as parasite death at 20 uM relative to control | Nippostrongylus brasiliensis | 9 | ALA4373637 | organism-based format | Scientific Literature | |
2. | ALA4373925 | B | Inhibition of wild type recombinant Echinococcus granulosus TGR at 50 uM preincubated for NADPH followed by compound addition and measured after 3 mins by spectrophotometric analysis relative to control | Echinococcus granulosus | 11 | ALA4373637 | single protein format | Scientific Literature | |
3. | ALA4373926 | F | Antiparasitic activity against Caenorhabditis elegans assessed as inhibition of parasite motility at 100 uM after 17.5 hrs by motility assay relative to control | Caenorhabditis elegans | 10 | ALA4373637 | organism-based format | Scientific Literature | |
4. | ALA4373927 | F | Antitrypanosomal activity against Trypanosoma brucei brucei 427 assessed as parasite death at 30 uM after 24 hrs by PI-staining based flow cytometry analysis relative to control | Trypanosoma brucei brucei | 10 | ALA4373637 | organism-based format | Scientific Literature | |
5. | ALA4373928 | F | Antitrypanosomal activity against Trypanosoma brucei brucei 427 assessed as parasite death at 5 uM after 24 hrs by PI-staining based flow cytometry analysis relative to control | Trypanosoma brucei brucei | 10 | ALA4373637 | organism-based format | Scientific Literature | |
6. | ALA4373929 | F | Antitrypanosomal activity against Trypanosoma brucei brucei 427 assessed as parasite death after 24 hrs by PI-staining based flow cytometry analysis | Trypanosoma brucei brucei | 8 | ALA4373637 | organism-based format | Scientific Literature | |
7. | ALA4373930 | A | Cytotoxicity against mouse J774 cells assessed as reduction in cell viability after 24 hrs by WST-1 assay | Mus musculus | 8 | ALA4373637 | cell-based format | Scientific Literature | |
8. | ALA4373931 | T | Selectivity index, ratio of EC50 for mouse J774 cells to EC50 for antitrypanosomal activity against Trypanosoma brucei brucei 427 | 8 | ALA4373637 | assay format | Scientific Literature |