| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4345255 | B | Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins followed by substrate addition and measured after 3 hrs by PPiLight Inorganic Pyrophosphate assay kit method | Homo sapiens | 44 | assay format | Scientific Literature | ||
| 2. | ALA4345256 | F | Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by celltiter glo assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4345281 | B | Inhibition of MTH1 in human U2OS cells assessed as 8-oxo-dGTP level per million cells at 20 uM incubated for 48 hrs by LC-MS/MS analysis (Rvb = 0.008 pmol) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4345282 | B | Inhibition of MTH1 in human U2OS cells assessed as 8-oxo-rGTP level per million cells at 20 uM incubated for 48 hrs by LC-MS/MS analysis (Rvb = 0.058 pmol) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4345283 | B | Inhibition of MTH1 in human U2OS cells assessed as dGTP level per million cells at 20 uM incubated for 48 hrs by LC-MS/MS analysis (Rvb = 17 pmol) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4345284 | B | Inhibition of MTH1 in human U2OS cells assessed as dGTP level per million cells at 20 uM incubated for 48 hrs by LC-MS/MS analysis (Rvb = 4370 pmol) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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