| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4341810 | B | Inhibition of N-terminal 6-His tagged full length Pin1 (unknown origin) expressed in Escherichia coli using Suc-AEPF-pNA as substrate preincubated for 10 mins followed by substrate addition and measured for 180 secs by spectrophotometry | Homo sapiens | 2 | ALA4340544 | assay format | Scientific Literature | |
| 2. | ALA4341811 | B | Inhibition of N-terminal 6-His tagged full length Pin1 (unknown origin) expressed in Escherichia coli at 10 uM using Suc-AEPF-pNA as substrate preincubated for 10 mins followed by substrate addition and measured for 180 secs by spectrophotometry relative to untreated control | Homo sapiens | 43 | ALA4340544 | assay format | Scientific Literature | |
| 3. | ALA4341812 | B | Inhibition of recombinant N-terminal His6-tagged Pin4 (unknown origin) expressed in Escherichia coli at 1 to 50 uM using Suc-AEPF-pNA as substrate preincubated for 10 min followed by substrate addition measured for 180 secs | Homo sapiens | 1 | ALA4340544 | assay format | Scientific Literature | |
| 4. | ALA4341813 | B | Inhibition of recombinant N-terminal His6-tagged FKBP12 (unknown origin) expressed in Escherichia coli at 1 to 50 uM using Suc-AEPF-pNA as substrate preincubated for 10 min followed by substrate addition measured for 180 secs | Homo sapiens | 1 | ALA4340544 | assay format | Scientific Literature | |
| 5. | ALA4341814 | B | Inhibition of recombinant N-terminal His6-tagged Cyclophilin A (unknown origin) expressed in Escherichia coli at 1 to 50 uM using Suc-AEPF-pNA as substrate preincubated for 10 min followed by substrate addition measured for 180 secs | Homo sapiens | 1 | ALA4340544 | assay format | Scientific Literature | |
| 6. | ALA4341815 | B | Inhibition of recombinant N-terminal His6-tagged Pin1 (unknown origin) expressed in Escherichia coli at 1 to 50 uM using Suc-AEPF-pNA as substrate preincubated for 10 min followed by substrate addition measured for 180 secs | Homo sapiens | 1 | ALA4340544 | assay format | Scientific Literature | |
| 7. | ALA4341816 | F | Cytotoxicity against human SKHEP1 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 1 | ALA4340544 | cell-based format | Scientific Literature | |
| 8. | ALA4341817 | F | Cytotoxicity against human SNU423 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 1 | ALA4340544 | cell-based format | Scientific Literature | |
| 9. | ALA4341818 | F | Cytotoxicity against human SKHEP1 cells assessed as reduction in cell viability at 5 to 25 uM measured up to 96 hrs by MTT assay | Homo sapiens | 1 | ALA4340544 | cell-based format | Scientific Literature | |
| 10. | ALA4341819 | F | Antiproliferation activity against human SKHEP1 cells assessed as reduction in colony formation at 2.5 uM measured after 7 days by crystal violet staining based microscopic analysis | Homo sapiens | 1 | ALA4340544 | cell-based format | Scientific Literature | |
| 11. | ALA4341820 | B | Inhibition of Pin1 in human SKHEP1 cells assessed as increase in cytoplasm distribution of XPO5 at 2.5 uM incubated for 36 hrs by DAPI staining based confocal microscopic analysis | Homo sapiens | 1 | ALA4340544 | cell-based format | Scientific Literature | |
| 12. | ALA4341821 | B | Inhibition of Pin1 in human SKHEP1 cells assessed as increase in miR-122 expression at 2.5 uM incubated for 36 hrs by quantitative RT PCR analysis | Homo sapiens | 1 | ALA4340544 | cell-based format | Scientific Literature | |
| 13. | ALA4341822 | B | Inhibition of Pin1 in human SKHEP1 cells assessed as increase in miR-29b expression at 2.5 uM incubated for 36 hrs by quantitative RT PCR analysis | Homo sapiens | 1 | ALA4340544 | cell-based format | Scientific Literature |
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