# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4345047 | B | Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells by fluorescence polarization assay | Homo sapiens | 6 | ALA4342482 | cell-based format | Scientific Literature | |
2. | ALA4345048 | B | Binding affinity to recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells assessed as increase in release of phosphate at 100 uM incubated for 10 mins by phosphate release assay | Homo sapiens | 6 | ALA4342482 | cell-based format | Scientific Literature | |
3. | ALA4345049 | B | Displacement of Ins(1,3,4,5)P4 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 2 | ALA4342482 | assay format | Scientific Literature | |
4. | ALA4345051 | B | Inhibition of recombinant human C-terminal His-tagged INPP5B (259 to 563 residues) expressed in Escherichia coli BL21 (DE3) incubated for 5 mins using Ins(1,4,5)P3 as substrate by malachite green reagent based phosphate assay | Homo sapiens | 2 | ALA4342482 | assay format | Scientific Literature | |
5. | ALA4345052 | B | Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assay | Homo sapiens | 6 | ALA4342482 | assay format | Scientific Literature |