| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4430306 | B | Inhibition of T-type alpha1G channel (unknown origin) expressed in HEK293 cells at 10 uM by fluorescence-based HTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA4430307 | B | Inhibition of T-type alpha1H channel (unknown origin) expressed in HEK293 cells at 10 uM by fluorescence-based HTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA4430308 | B | Inhibition of T-type alpha1G channel (unknown origin) by whole cell patch clamp method | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 4. | ALA4430309 | B | Inhibition of T-type alpha1H channel (unknown origin) by whole cell patch clamp method | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 5. | ALA4430310 | B | Inhibition of N-type calcium channel (unknown origin) at 10 uM by whole cell patch clamp method | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 6. | ALA4430311 | B | Inhibition of human ERG expressed in CHO-K1 cells by whole cell patch clamp method | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA4430312 | A | Inhibition of human CYP2D6 expressed in baculosomes assessed as remaining activity using fluorogenic substrate after 15 mins in presence of NADPH by fluorescence assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 8. | ALA4430313 | A | Inhibition of human CYP2C9 expressed in baculosomes assessed as remaining activity using fluorogenic substrate after 15 mins in presence of NADPH by fluorescence assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 9. | ALA4430314 | A | Inhibition of human CYP2C19 expressed in baculosomes assessed as remaining activity using fluorogenic substrate after 15 mins in presence of NADPH by fluorescence assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 10. | ALA4430315 | A | Inhibition of human CYP3A4 expressed in baculosomes assessed as remaining activity using fluorogenic substrate after 15 mins in presence of NADPH by fluorescence assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 11. | ALA4430316 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining after 30 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 12. | ALA4430317 | F | Antiallodynic activity in rat model of spinal nerve ligation-induced neuropathic pain assessed as reduction in mechanical threshold for paw withdrawal at 100 mg/kg, po administered on day 14 after ligation surgery and measured 3 to 5 hrs post dose by Von Frey filaments based method | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA4430318 | F | Antiallodynic activity in rat model of spinal nerve ligation-induced neuropathic pain assessed as reduction in cold allodynia by measuring paw withdrawal in response to acetone application at 100 mg/kg, po administered on day 14 after ligation surgery measured 1 to 5 hrs post dose relative to gabapentin | Rattus norvegicus | 2 | organism-based format | Scientific Literature |
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