#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4418717	Binding	Substrate activity at LRAT in bovine RPE microsomes at 1 mM incubated for 1 hr at 37 degC by HPLC analysis relative to corresponding primary alcohols	Bos taurus	36	ALA4418488	assay format	Patent Bioactivity Data
2.	ALA4418718	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as effect on thickness of outer nuclear layer at 1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by SDOCT and ERG analysis	Mus musculus	12	ALA4418488	organism-based format	Patent Bioactivity Data
3.	ALA4418719	Binding	Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production pre-incubated at room temperature for 5 mins before all-trans-retinol addition and further incubated for 15 mins to 2 hrs in presence of CRALBP by normal phase HPLC analysis	Bos taurus	36	ALA4418488	assay format	Patent Bioactivity Data
4.	ALA4418720	Toxicity	Toxicity in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse model of intense light-induced retinal degeneration at 1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by SDOCT and ERG analysis	Mus musculus	12	ALA4418488	organism-based format	Patent Bioactivity Data
5.	ALA4418723	Functional	Protective effect against intense light-induced retinal degeneration in wild type mouse assessed as rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.2 mg pretreated with compound followed by exposure to light illumination 2 hrs after compound dosing (Rvb = 85 +/- 5%) by HPLC analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
6.	ALA4418724	Functional	Protective effect against intense light-induced retinal degeneration in wild type mouse assessed as rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.2 mg pretreated with compound followed by exposure to light illumination 24 hrs after compound dosing (Rvb = 85 +/- 5%) by HPLC analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
7.	ALA4418725	Functional	Protective effect against intense light-induced retinal degeneration in wild type mouse assessed as rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.2 mg pretreated with compound followed by exposure to light illumination 3 days after compound dosing (Rvb = 85 +/- 5%) by HPLC analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
8.	ALA4418726	Functional	Protective effect against intense light-induced retinal degeneration in wild type mouse assessed as rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.2 mg pretreated with compound followed by exposure to light illumination 7 days after compound dosing (Rvb = 85 +/- 5%) by HPLC analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
9.	ALA4418727	Functional	Protective effect against intense light-induced retinal degeneration in wild type mouse assessed as rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.5 mg pretreated with compound followed by exposure to light illumination 7 days after compound dosing (Rvb = 85 +/- 5%) by HPLC analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
10.	ALA4418728	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by HPLC analysis relative to control	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
11.	ALA4418729	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.2 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by HPLC analysis relative to control	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
12.	ALA4418730	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level in eye at 0.5 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr by HPLC analysis relative to control	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
13.	ALA4418731	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse at 0.1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 3 days by OCT analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
14.	ALA4418732	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as ONL thickness at 0.5 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 3 days by OCT analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
15.	ALA4418733	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as ONL thickness at 0.2 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 3 days by OCT analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
16.	ALA4418734	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level per eye at 0.2 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 7 days by HPLC analysis (Rvb = 452 +/-43 pmol/eye)	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
17.	ALA4418735	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse assessed as inhibition of rate of visual chromophore recovery by measuring 11-cis- retinal level per eye at 0.1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 7 days by HPLC analysis (Rvb = 301+/- 8 pmol/eye)	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
18.	ALA4418736	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse at 0.2 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 3 days by ERG analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
19.	ALA4418737	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse at 0.5 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 3 days by ERG analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data
20.	ALA4418738	Functional	Protective effect against intense light-induced retinal degeneration in 4 weeks old Abca4(-/-)/Rdh8 (-/-) mouse at 0.1 mg dosed via gavage under dark for 24 hrs before exposure to 10000 lux bright light for 1 hr followed by exposure to dark for 3 days by ERG analysis	Mus musculus	1	ALA4418488	organism-based format	Patent Bioactivity Data