# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4394894 | Binding | Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by pyruvate kinase-lactate dehydrogenase coupled UV-vis spectrophotometric method | Mycobacterium tuberculosis H37Rv | 17 | ALA4393679 | assay format | Scientific Literature | |
2. | ALA4394897 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis MC2 7000 after 6 days by micro plate alamar blue assay | Mycobacterium tuberculosis | 13 | ALA4393679 | organism-based format | Scientific Literature | |
3. | ALA4394898 | ADME | Cytotoxicity against HDF cells assessed as reduction in cell viability measured after 48 hrs by resazurin dye-based assay | Homo sapiens | 13 | ALA4393679 | cell-based format | Scientific Literature | |
4. | ALA4394901 | ADME | Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by pyruvate kinase-lactate dehydrogenase-coupled UV-vis spectrophotometric assay | Homo sapiens | 12 | ALA4393679 | assay format | Scientific Literature |