# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4394179 | Binding | Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition for 30 secs and measured after 1 hr by microplate reader based enzyme immunoassay | Homo sapiens | 15 | ALA4393660 | single protein format | Scientific Literature | |
2. | ALA4394180 | Binding | Inhibition of human recombinant COX-2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition for 30 secs and measured after 1 hr by microplate reader based enzyme immunoassay | Homo sapiens | 15 | ALA4393660 | single protein format | Scientific Literature | |
3. | ALA4394183 | Binding | Selectivity index, ratio of IC50 for human recombinant COX1 to IC50 for human recombinant COX-2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition for 30 secs and measured after 1 hr by microplate reader based enzyme immunoassay | Homo sapiens | 15 | ALA4393660 | assay format | Scientific Literature |