Effect on triglyceride accumulation in Sprague-Dawley rat high fat dietary model at 3 mg/kg, po assessed as reduction in triglyceride level after 42 days by XPT clinical analyzer
Effect on triglyceride accumulation in Sprague-Dawley rat high fat dietary model at 1 mg/kg, po assessed as reduction in triglyceride level after 42 days by XPT clinical analyzer
Effect on triglyceride accumulation in Sprague-Dawley rat high fat dietary model at 10 mg/kg, po assessed as reduction in triglyceride level after 42 days by XPT clinical analyzer
Effect on triglyceride accumulation in po dosed Sprague-Dawley rat high fat dietary model assessed as reduction in triglyceride level after 42 days by XPT clinical analyzer
Inhibition of DNL in Sprague-Dawley rat assessed as reduction in DNL level in bone marrow at 300 mg/kg, po pretreated with 1 hr followed by [14C]-acetate treatment and measured after 1 hr relative to control
Inhibition of DNL in Sprague-Dawley rat assessed as reduction in DNL level in lung at 300 mg/kg, po pretreated with 1 hr followed by [14C]-acetate treatment and measured after 1 hr relative to control
Inhibition of DNL in po dosed Sprague-Dawley rat assessed as reduction in DNL level in liver pretreated with one hr followed by [14C]-acetate treatment and measured after 1 hr
Inhibition of DNL in Sprague-Dawley rat assessed as reduction in DNL level in liver at 300 mg/kg, po pretreated with one hr followed by [14C]-acetate treatment and measured after 1 hr relative to control