| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4353986 | B | Inhibition of human recombinant C-terminal His/FLAG-tagged HDAC1 using Boc-Lys-(epsilon-Ac)-AMC as fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 2. | ALA4353987 | B | Inhibition of human recombinant C-terminal FLAG-tagged HDAC2 using Boc-Lys-(epsilon-Ac)-AMC as fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 3. | ALA4353988 | B | Inhibition of human recombinant C-terminal His-tagged HDAC3/NCOR2 using Boc-Lys-(epsilon-Ac)-AMC as fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 11 | protein complex format | Scientific Literature | ||
| 4. | ALA4353989 | B | Selectivity ratio of IC50 for human recombinant C-terminal His-tagged HDAC3/NCOR2 to IC50 for human recombinant C-terminal His/FLAG-tagged HDAC1 | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 5. | ALA4353990 | B | Selectivity ratio of IC50 for human recombinant C-terminal His-tagged HDAC3/NCOR2 to IC50 for human recombinant C-terminal FLAG-tagged HDAC2 | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 6. | ALA4353991 | A | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 1 to 5 uM incubated for 24 hrs by MTS assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA4354007 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of TNF-alpha gene expression at pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4354008 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of IL-6 gene expression at pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4354009 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of iNOS gene expression at pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4354010 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of IL-10 gene expression at pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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