| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4381106 | B | Binding affinity to DNA (unknown origin) strands containing 95 and 89 nucleotides in ratio of 1:2 assessed as interaction between G4 motif of 95 nucleotides and biotinylated compound at 0.2 to 0.4 uM at pH 7.4 after 1 hr by biotin-streptavidin pull-down assay | Not specified | 1 | nucleic acid format | Scientific Literature | ||
| 2. | ALA4381107 | B | Binding affinity to DNA (unknown origin) strands containing 95 and 89 nucleotides in ratio of 1:2 assessed as presence of ssDNA when G4 motif of 95 nucleotides interact with biotinylated compound at > 0.4 uM at pH 7.4 after 1 hr by biotin-streptavidin pull-down assay | Not specified | 1 | nucleic acid format | Scientific Literature | ||
| 3. | ALA4381108 | B | Binding affinity to total RNA in human PANC1 cells assessed as increase in amount of KRAS mRNA in recovered RNA from biotin-streptavidin pulled down at 0.2 to 0.6 uM at pH 7.4 and 4 degree C using biotinylated compound by qRT-PCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4381109 | B | Binding affinity to total RNA in human PANC1 cells assessed as increase in amount of HPRT mRNA in recovered RNA from biotin-streptavidin pulled down at 0.2 to 0.6 uM at pH 7.4 and 4 degree C using biotinylated compound by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4381110 | B | Binding affinity to total RNA in human PANC1 cells assessed as increase in amount of beta2-microglobulin mRNA in recovered RNA from biotin-streptavidin pulled down at 0.2 to 0.6 uM at pH 7.4 and 4 degree C using biotinylated compound by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4381111 | B | Binding affinity to total RNA in human PANC1 cells assessed as increase in amount of NRAS mRNA in recovered RNA from biotin-streptavidin pulled down at 0.2 to 0.6 uM at pH 7.4 and 4 degree C using biotinylated compound by qRT-PCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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