| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4334911 | B | Inhibition of human GSK-3alpha S449A mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by scintillation counting method relative to control | Homo sapiens | 80 | ALA4334438 | single protein format | Scientific Literature | |
| 2. | ALA4334912 | B | Inhibition of human GSK-3alpha S449A mutant (2 to end residues) using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by scintillation counting method | Homo sapiens | 54 | ALA4334438 | single protein format | Scientific Literature | |
| 3. | ALA4334913 | A | Inhibition of human GSK-3beta H350L mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins by [gamma-33ATP] radiometric assay relative to control | Homo sapiens | 48 | ALA4334438 | single protein format | Scientific Literature | |
| 4. | ALA4334914 | A | Inhibition of human GSK-3beta H350L mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins by [gamma-33ATP] radiometric assay | Homo sapiens | 48 | ALA4334438 | single protein format | Scientific Literature | |
| 5. | ALA4334915 | B | Selectivity index, ratio of IC50 for inhibition of human GSK-3beta H350L mutant (2 to end residues) to IC50 for inhibition of human GSK-3alpha S449A mutant (2 to end residues) | Homo sapiens | 3 | ALA4334438 | assay format | Scientific Literature | |
| 6. | ALA4334916 | F | Antiproliferative activity against human HL60 cells assessed as reduction in viability after 3 days by SRB assay | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
| 7. | ALA4334917 | F | Antiproliferative activity against human NB4 cells assessed as reduction in viability after 3 days by SRB assay | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
| 8. | ALA4334920 | F | Inhibition of colony formation in human HL60 cells preincubated for 72 hrs followed by compound washout and measured after 7 to 10 days | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
| 9. | ALA4334921 | F | Inhibition of colony formation in human NB4 cells preincubated for 72 hrs followed by compound washout and measured after 7 to 10 days | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
| 10. | ALA4334924 | A | Induction of cell death in human HL60 cells at 10 to 30 uM after 6 days by trypan blue assay | Homo sapiens | 1 | ALA4334438 | cell-based format | Scientific Literature | |
| 11. | ALA4334925 | A | Induction of cell death in human NB4 cells at 10 to 30 uM after 6 days by trypan blue assay | Homo sapiens | 1 | ALA4334438 | cell-based format | Scientific Literature | |
| 12. | ALA4334926 | F | Induction of cell differentiation in human HL60 cells assessed as increase in CD11b-APC-Cy7 positive cells after 6 days by flow cytometry analysis | Homo sapiens | 1 | ALA4334438 | cell-based format | Scientific Literature | |
| 13. | ALA4334927 | F | Induction of cell differentiation in human NB4 cells assessed as increase in CD11b-APC-Cy7 positive cells after 6 days by flow cytometry analysis | Homo sapiens | 1 | ALA4334438 | cell-based format | Scientific Literature | |
| 14. | ALA4334928 | F | Induction of cell differentiation in human HL60 cells assessed as increase in CD11c-APC positive cells after 6 days by flow cytometry analysis | Homo sapiens | 1 | ALA4334438 | cell-based format | Scientific Literature | |
| 15. | ALA4334929 | F | Induction of cell differentiation in human NB4 cells assessed as increase in CD11c-APC positive cells after 6 days by flow cytometry analysis | Homo sapiens | 1 | ALA4334438 | cell-based format | Scientific Literature | |
| 16. | ALA4334930 | F | Induction of cell differentiation in human HL60 cells assessed as increase in CD14-FITC positive cells after 6 days by flow cytometry analysis | Homo sapiens | 1 | ALA4334438 | cell-based format | Scientific Literature | |
| 17. | ALA4334931 | F | Induction of cell differentiation in human NB4 cells assessed as increase in CD14-FITC positive cells after 6 days by flow cytometry analysis | Homo sapiens | 1 | ALA4334438 | cell-based format | Scientific Literature | |
| 18. | ALA4334932 | F | Induction of monocytic differentiation in human HL60 cells assessed as increase in CD11b-APC-Cy7 positive cells at 30 uM after 6 days by flow cytometry analysis | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
| 19. | ALA4334933 | F | Induction of monocytic differentiation in human NB4 cells assessed as increase in CD11b-APC-Cy7 positive cells at 30 uM after 6 days by flow cytometry analysis | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature | |
| 20. | ALA4334934 | F | Induction of monocytic differentiation in human HL60 monocytic assessed as increase in CD11c-APC positive cells at 30 uM after 6 days by flow cytometry analysis | Homo sapiens | 2 | ALA4334438 | cell-based format | Scientific Literature |
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