# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4380225 | ADME | Substrate activity at Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli BL21 (DE3) assessed as retention time by HPLC analysis | Staphylococcus saprophyticus | 36 | ALA4376859 | assay format | Scientific Literature | |
2. | ALA4380257 | Functional | Cytotoxicity against human PC3 cells expressing Staphylococcus saprophyticus nitroreductase NtrB assessed as reduction in cell viability in presence of NADH as cofactor after 48 hrs by SRB assay | Homo sapiens | 21 | ALA4376859 | cell-based format | Scientific Literature | |
3. | ALA4380259 | Functional | Cytotoxicity against human Hep3B cells assessed as cell viability at 9 to 150 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 31 | ALA4376859 | cell-based format | Scientific Literature | |
4. | ALA4380260 | Functional | Cytotoxicity against human Hep3B cells assessed as cell viability at 9 to 150 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 29 | ALA4376859 | cell-based format | Scientific Literature | |
5. | ALA4380261 | Functional | Cytotoxicity against human PC3 cells assessed as cell viability at 9 to 150 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 27 | ALA4376859 | cell-based format | Scientific Literature | |
6. | ALA4380262 | Functional | Cytotoxicity against human PC3 cells assessed as cell viability at 9 to 150 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 26 | ALA4376859 | cell-based format | Scientific Literature | |
7. | ALA4380263 | ADME | Cytotoxicity against human HUVEC cells assessed as cell viability at 9 to 150 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 35 | ALA4376859 | cell-based format | Scientific Literature | |
8. | ALA4380264 | ADME | Cytotoxicity against human HUVEC cells assessed as cell viability at 9 to 150 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 35 | ALA4376859 | cell-based format | Scientific Literature | |
9. | ALA4380265 | ADME | Substrate activity at Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli BL21 (DE3) assessed as enzyme mediated reduction at 50 to 150 uM measured up 20 hrs by HPLC analysis in presence of NADPH | Staphylococcus saprophyticus | 36 | ALA4376859 | assay format | Scientific Literature | |
10. | ALA4380266 | Functional | Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by SRB assay | Homo sapiens | 25 | ALA4376859 | cell-based format | Scientific Literature |