# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4333693 | Binding | Inhibition of BRAF V600E mutant (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA4330133 | single protein format | Scientific Literature | |
2. | ALA4333694 | Binding | Inhibition of BRAF V600E mutant (unknown origin) | Homo sapiens | 14 | ALA4330133 | single protein format | Scientific Literature | |
3. | ALA4333695 | Binding | Inhibition of CRAF (unknown origin) | Homo sapiens | 18 | ALA4330133 | single protein format | Scientific Literature | |
4. | ALA4333696 | Binding | Inhibition of CRAF (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA4330133 | single protein format | Scientific Literature | |
5. | ALA4333697 | ADME | Inhibition of wild-type BRAF (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA4330133 | single protein format | Scientific Literature | |
6. | ALA4333698 | ADME | Inhibition of wild-type BRAF (unknown origin) | Homo sapiens | 1 | ALA4330133 | single protein format | Scientific Literature | |
7. | ALA4333699 | Functional | Growth inhibition of human A375 cells expressing BRAF V600E mutant by MTT assay | Homo sapiens | 1 | ALA4330133 | cell-based format | Scientific Literature | |
8. | ALA4333700 | ADME | Growth inhibition of human SW620 cells expressing wild-type BRAF by MTT assay | Homo sapiens | 1 | ALA4330133 | cell-based format | Scientific Literature | |
9. | ALA4333701 | Binding | Selectivity ratio of IC50 for wild-type BRAF (unknown origin) to IC50 for BRAF V600E mutant (unknown origin) | Homo sapiens | 1 | ALA4330133 | assay format | Scientific Literature | |
10. | ALA4333702 | Binding | Selectivity ratio of IC50 for wild-type BRAF (unknown origin) to IC50 for CRAF (unknown origin) | Homo sapiens | 1 | ALA4330133 | assay format | Scientific Literature |