# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4321142 | Binding | Inhibition of topoisomerase 2 in human HepG2 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay | Homo sapiens | 21 | ALA4316614 | cell-based format | Scientific Literature | |
2. | ALA4321143 | Binding | Inhibition of topoisomerase 2 in human HeLa cells assessed as reduction in cell growth measured after 72 hrs by MTT assay | Homo sapiens | 21 | ALA4316614 | cell-based format | Scientific Literature | |
3. | ALA4321144 | Binding | Inhibition of topoisomerase 2 in human A549 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay | Homo sapiens | 21 | ALA4316614 | cell-based format | Scientific Literature | |
4. | ALA4321145 | Binding | Inhibition of topoisomerase 2 in human CNE1 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay | Homo sapiens | 21 | ALA4316614 | cell-based format | Scientific Literature | |
5. | ALA4321146 | Binding | Inhibition of topoisomerase 2 in human MCF7 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay | Homo sapiens | 21 | ALA4316614 | cell-based format | Scientific Literature | |
6. | ALA4321147 | Binding | Inhibition of topoisomerase 2 in human MDA-MB-231 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay | Homo sapiens | 21 | ALA4316614 | cell-based format | Scientific Literature | |
7. | ALA4321148 | ADME | Cytotoxicity against human L02 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay | Homo sapiens | 21 | ALA4316614 | cell-based format | Scientific Literature | |
8. | ALA4321149 | Functional | Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth measured by MTT assay | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
9. | ALA4321150 | Functional | Induction of apoptosis in human HepG2 cells measured after 48 hrs by Annexin V-APC staining based flow cytometry | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
10. | ALA4321151 | Functional | Induction of apoptosis in human HepG2 cells assessed as apoptotic cells at 4 uM measured after 48 hrs by Annexin V-APC staining based flow cytometry (Rvb = 5.37%) | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
11. | ALA4321152 | Functional | Induction of apoptosis in human HepG2 cells assessed as apoptotic cells at 8 uM measured after 48 hrs by Annexin V-APC staining based flow cytometry (Rvb = 5.37%) | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
12. | ALA4321153 | Functional | Induction of apoptosis in human HepG2 cells assessed as apoptotic cells at 16 uM measured after 48 hrs by Annexin V-APC staining based flow cytometry (Rvb = 5.37%) | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
13. | ALA4321154 | Functional | Induction of apoptosis in human HepG2 cells assessed as apoptotic cells at 32 uM measured after 48 hrs by Annexin V-APC staining based flow cytometry (Rvb = 5.37%) | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
14. | ALA4321155 | Functional | Induction of apoptosis in human HepG2 cells assessed as cell shrinkage at 4 to 16 uM measured after 48 hrs by Hoechst 33342 staining based fluorescence microscopic analysis | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
15. | ALA4321156 | Functional | Induction of apoptosis in human HepG2 cells assessed as formation of granular apoptotic body formation at 4 to 16 uM measured after 48 hrs by Hoechst 33342 staining based fluorescence microscopic analysis | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
16. | ALA4321157 | ADME | Drug uptake in cytoplasm of human HepG2 cells at 2 to 16 uM by confocal microscopic analysis | Homo sapiens | 1 | ALA4316614 | subcellular format | Scientific Literature | |
17. | ALA4321158 | ADME | Drug uptake in nucleus of human HepG2 cells at 2 to 16 uM by confocal microscopic analysis | Homo sapiens | 1 | ALA4316614 | subcellular format | Scientific Literature | |
18. | ALA4321159 | Functional | Induction of morphological changes in human HepG2 cells assessed as nuclear shrinkage at 2 to 16 uM by confocal microscopic analysis | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
19. | ALA4321160 | Functional | Induction of morphological changes in human HepG2 cells assessed as nuclear deformation at 2 to 16 uM by confocal microscopic analysis | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature | |
20. | ALA4321161 | Functional | Induction of morphological changes in human HepG2 cells assessed as appearance of foamy nucleus at 2 to 16 uM by confocal microscopic analysis | Homo sapiens | 1 | ALA4316614 | cell-based format | Scientific Literature |