# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4370283 | Functional | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA4368913 | cell-based format | Scientific Literature | |
2. | ALA4370284 | Functional | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA4368913 | cell-based format | Scientific Literature | |
3. | ALA4370285 | Functional | Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA4368913 | cell-based format | Scientific Literature | |
4. | ALA4370286 | Functional | Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA4368913 | cell-based format | Scientific Literature | |
5. | ALA4370287 | Functional | Antiproliferative activity against human RS4:11 cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA4368913 | cell-based format | Scientific Literature | |
6. | ALA4370288 | Binding | Inhibition of bovine brain tubulin polymerization after 20 mins | Bos taurus | 8 | ALA4368913 | assay format | Scientific Literature | |
7. | ALA4370289 | Binding | Inhibition of [3H]-colchicine binding to bovine brain tubulin at 1 to 5 uM after 20 mins relative to control | Bos taurus | 8 | ALA4368913 | assay format | Scientific Literature | |
8. | ALA4370290 | Binding | Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assay | Homo sapiens | 9 | ALA4368913 | single protein format | Scientific Literature | |
9. | ALA4370291 | Binding | Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assay | Homo sapiens | 5 | ALA4368913 | single protein format | Scientific Literature | |
10. | ALA4370292 | Binding | Inhibition of EGF-induced EGFR phosphorylation at Y1068 in human HeLa cells pretreated for 6 hrs followed by EGF cells and measured after 15 mins by Western blot analysis | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
11. | ALA4370293 | Binding | Inhibition of EGF-induced EGFR phosphorylation at Y1068 in human HeLa cells at 1 uM pretreated for 6 hrs followed by EGF cells and measured after 15 mins by Western blot analysis | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
12. | ALA4370294 | Functional | Induction of cell cycle arrest in human HeLa cells assessed as arrest in mitotic phase at 50 nM after 24 hrs by p-histone H3 antibody staining based flow cytometry (Rvb = 1.32%) | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
13. | ALA4370295 | Functional | Induction of cell cycle arrest in human HeLa cells assessed as arrest in mitotic phase at 100 nM after 24 hrs by p-histone H3 antibody staining based flow cytometry (Rvb = 1.32%) | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
14. | ALA4370296 | Functional | Induction of apoptosis in human HeLa cells at 50 nM after 24 to 48 hrs by Annexin V/propidium iodide-double staining-based flow cytometry | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
15. | ALA4370297 | Functional | Induction of apoptosis in human Jurkat cells at 50 nM after 24 to 48 hrs by Annexin V/propidium iodide-double staining-based flow cytometry | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
16. | ALA4370298 | Functional | Induction of mitochondrial membrane depolarization in human HeLa cells by JC1-staining based flow cytometry | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
17. | ALA4370299 | Functional | Induction of ROS generation in human HeLa cells at 50 nM after 12 hrs by 2,7-dichlorodihydrofluorescein diacetate-staining based flow cytometry | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
18. | ALA4370300 | Functional | Induction of apoptosis in human HeLa cells assessed as increase in cleaved PARP expression by Western blot analysis | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
19. | ALA4370301 | Functional | Induction of apoptosis in human HeLa cells assessed as decrease in bcl2 expression at 50 to 100 nM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature | |
20. | ALA4370302 | Functional | Induction of apoptosis in human HeLa cells assessed as decrease in mcl2 expression at 50 to 100 nM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4368913 | cell-based format | Scientific Literature |