# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4334051 | Functional | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay | Homo sapiens | 32 | ALA4330150 | cell-based format | Scientific Literature | |
2. | ALA4334052 | Functional | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 32 | ALA4330150 | cell-based format | Scientific Literature | |
3. | ALA4334053 | Functional | Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay | Homo sapiens | 32 | ALA4330150 | cell-based format | Scientific Literature | |
4. | ALA4334054 | ADME | Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay | Homo sapiens | 3 | ALA4330150 | cell-based format | Scientific Literature | |
5. | ALA4334055 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at sub-G1 phase at 2.5 uM after 48 hrs by propidium iodide staining based FACS analysis (Rvb = 1.69%) | Homo sapiens | 2 | ALA4330150 | cell-based format | Scientific Literature | |
6. | ALA4334056 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at G1 phase at 2.5 uM after 48 hrs by propidium iodide staining based FACS analysis (Rvb = 73.5%) | Homo sapiens | 2 | ALA4330150 | cell-based format | Scientific Literature | |
7. | ALA4334057 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at S phase at 2.5 uM after 48 hrs by propidium iodide staining based FACS analysis (Rvb = 5.58%) | Homo sapiens | 2 | ALA4330150 | cell-based format | Scientific Literature | |
8. | ALA4334058 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at G2/M phase at 2.5 uM after 48 hrs by propidium iodide staining based FACS analysis (Rvb = 13.9%) | Homo sapiens | 2 | ALA4330150 | cell-based format | Scientific Literature | |
9. | ALA4334059 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at sub-G1 phase at 5 uM after 48 hrs by propidium iodide staining based FACS analysis (Rvb = 1.69%) | Homo sapiens | 2 | ALA4330150 | cell-based format | Scientific Literature | |
10. | ALA4334060 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at G1 phase at 5 uM after 48 hrs by propidium iodide staining based FACS analysis (Rvb = 73.5%) | Homo sapiens | 2 | ALA4330150 | cell-based format | Scientific Literature | |
11. | ALA4334061 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at S phase at 5 uM after 48 hrs by propidium iodide staining based FACS analysis (Rvb = 5.58%) | Homo sapiens | 2 | ALA4330150 | cell-based format | Scientific Literature | |
12. | ALA4334062 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at G2/M phase at 5 uM after 48 hrs by propidium iodide staining based FACS analysis (Rvb = 13.9%) | Homo sapiens | 2 | ALA4330150 | cell-based format | Scientific Literature | |
13. | ALA4334063 | Binding | Binding affinity to calf thymus DNA assessed as hypochromicity at 10 uM by UV-Visible spectrophotometric method | Bos taurus | 3 | ALA4330150 | nucleic acid format | Scientific Literature | |
14. | ALA4334064 | Binding | Binding affinity to calf thymus DNA assessed as hypochromicity shift at 10 uM by fluorescence spectral analysis | Bos taurus | 3 | ALA4330150 | nucleic acid format | Scientific Literature | |
15. | ALA4334065 | Binding | Binding affinity to calf thymus DNA assessed as hypochromicity shift in positive band at DNA to compound ratio of 1:1 by CD spectral analysis | Bos taurus | 3 | ALA4330150 | nucleic acid format | Scientific Literature | |
16. | ALA4334066 | Binding | Binding affinity to calf thymus DNA assessed as hypochromicity shift in positive band at DNA to compound ratio of 1:2 by CD spectral analysis | Bos taurus | 3 | ALA4330150 | nucleic acid format | Scientific Literature | |
17. | ALA4334067 | Binding | Binding affinity to calf thymus DNA assessed as hypochromicity shift in negative band at DNA to compound ratio of 1:1 to 1:2 by CD spectral analysis | Bos taurus | 3 | ALA4330150 | nucleic acid format | Scientific Literature | |
18. | ALA4334068 | Binding | Binding affinity to calf thymus DNA assessed as DNA intercalation by measuring increase in viscosity at 15 uM by Ostwald viscometric method | Bos taurus | 3 | ALA4330150 | nucleic acid format | Scientific Literature | |
19. | ALA4334070 | Binding | Inhibition of topoisomerase-1 (unknown origin) at 100 uM using pBR322 DNA as substrate after 30 mins by agarose gel electrophoresis method | Homo sapiens | 3 | ALA4330150 | single protein format | Scientific Literature |