#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4345255	Binding	Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins followed by substrate addition and measured after 3 hrs by PPiLight Inorganic Pyrophosphate assay kit method	Homo sapiens	44	ALA4342490	assay format	Scientific Literature
2.	ALA4345256	Functional	Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by celltiter glo assay	Homo sapiens	8	ALA4342490	cell-based format	Scientific Literature
3.	ALA4345259	ADME	Permeability across apical to basolateral side in human Caco2 cells	Homo sapiens	3	ALA4342490	cell-based format	Scientific Literature
4.	ALA4345260	ADME	Permeability across basolateral to apical side in human Caco2 cells	Homo sapiens	3	ALA4342490	cell-based format	Scientific Literature
5.	ALA4345265	Physicochemical	Kinetic solubility of compound at pH 2		2	ALA4342490	small-molecule physicochemical format	Scientific Literature
6.	ALA4345266	Physicochemical	Kinetic solubility of compound at pH 7		2	ALA4342490	small-molecule physicochemical format	Scientific Literature
7.	ALA4345270	ADME	Oral bioavailability in Sprague-Dawley rat at 5 mg/kg	Rattus norvegicus	1	ALA4342490	organism-based format	Scientific Literature
8.	ALA4345271	ADME	Clearance in Sprague-Dawley rat at 5 mg/kg, po or 1 mg/kg, iv	Rattus norvegicus	1	ALA4342490	organism-based format	Scientific Literature
9.	ALA4345272	ADME	Volume of distribution in Sprague-Dawley rat at 5 mg/kg, po or 1 mg/kg, iv	Rattus norvegicus	1	ALA4342490	organism-based format	Scientific Literature
10.	ALA4345273	ADME	Half life in Sprague-Dawley rat at 5 mg/kg, po or 1 mg/kg, iv	Rattus norvegicus	1	ALA4342490	organism-based format	Scientific Literature
11.	ALA4345274	Binding	Inhibition of human ERG	Homo sapiens	1	ALA4342490	single protein format	Scientific Literature
12.	ALA4345275	ADME	Inhibition of CYP isoform (unknown origin)	Homo sapiens	1	ALA4342490	protein format	Scientific Literature
13.	ALA4345276	Binding	Activation of human PXR at 15 uM	Homo sapiens	1	ALA4342490	single protein format	Scientific Literature
14.	ALA4345277	ADME	Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 72 hrs by celltiter glo assay	Homo sapiens	3	ALA4342490	cell-based format	Scientific Literature
15.	ALA4345278	Binding	Inhibition of MTH1 in human U2OS cells assessed as activation of p53 at 5 uM incubated for 4 and 24 hrs by Peggy sue Western blot assay	Homo sapiens	4	ALA4342490	cell-based format	Scientific Literature
16.	ALA4345280	Functional	Induction of DNA damage in human U2OS cells assessed as increase in gammaH2AX foci formation at 20 uM incubated for 72 hrs by immunostaining based confocal microscopy	Homo sapiens	4	ALA4342490	cell-based format	Scientific Literature