| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4377380 | B | Inhibition of JAK1/TYK2 in human Kit225 T cells assessed as inhibition of STAT phosphorylation by luciferase reporter assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 2. | ALA4377381 | B | Inhibition of TYK2 in human whole blood assessed as decrease in IFNalpha-induced STAT5 phosphorylation preincubated for 1 hr followed by stimulation with IFN-alpha for 15 mins by fluorescence analysis | Homo sapiens | 31 | tissue-based format | Scientific Literature | ||
| 3. | ALA4377382 | B | Inhibition of TYK2 in mouse whole blood assessed as decrease in IFNalpha-induced STAT1 phosphorylation preincubated for 1 hr followed by stimulation with IFN-alpha for 15 mins by fluorescence analysis | Mus musculus | 15 | tissue-based format | Scientific Literature | ||
| 4. | ALA4377383 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining incubated for 10 mins | Mus musculus | 15 | microsome format | Scientific Literature | ||
| 5. | ALA4377384 | A | Permeability coefficient, Kp across apical to basolateral side in human Caco2 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA4377385 | B | Inhibition of human ERG by in vitro patch clamp method | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 7. | ALA4377386 | A | Metabolic stability in mouse liver microsomes assessed as half life | Mus musculus | 2 | microsome format | Scientific Literature |
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