| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4406024 | B | Displacement of [3H]R-PIA from recombinant human A1AR expressed in HEK293 cell membranes at 10 uM measured after 60 mins by liquid scintillation counting method relative to control | Homo sapiens | 19 | ALA4402597 | cell-based format | Scientific Literature | |
| 2. | ALA4406025 | B | Displacement of [3H]R-PIA from recombinant mouse A1AR expressed in HEK293 cell membranes measured after 60 mins by liquid scintillation counting method | Mus musculus | 4 | ALA4402597 | cell-based format | Scientific Literature | |
| 3. | ALA4406027 | B | Displacement of [3H]CGS21680 from recombinant human A2AAR expressed in HEK293 cell membranes at 10 uM measured after 60 mins by liquid scintillation counting method relative to control | Homo sapiens | 24 | ALA4402597 | cell-based format | Scientific Literature | |
| 4. | ALA4406028 | B | Displacement of [125I]I-AB-MECA from recombinant human A3AR expressed in HEK293 cell membranes measured after 60 mins by liquid scintillation counting method | Homo sapiens | 25 | ALA4402597 | cell-based format | Scientific Literature | |
| 5. | ALA4406029 | B | Displacement of [125I]I-AB-MECA from recombinant mouse A3AR expressed in HEK293 cell membranes measured after 60 mins by liquid scintillation counting method | Mus musculus | 25 | ALA4402597 | cell-based format | Scientific Literature | |
| 6. | ALA4406032 | F | Partial agonist activity at recombinant mouse A3AR expressed in HEK293 cell membranes assessed as stimulation of [35S]GTPgammaS binding measured after 2 hrs in presence of A2BAR blocker PSB-603 by liquid scintillation counting analysis relative to adenosine-5'-Nethyluronamide | Mus musculus | 2 | ALA4402597 | cell-based format | Scientific Literature | |
| 7. | ALA4406034 | F | Partial agonist activity at recombinant human A3AR expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by measuring residual cAMP level measured after 30 mins in presence of A2BAR blocker PSB-603 by Glo-sensor assay relative to control | Homo sapiens | 4 | ALA4402597 | cell-based format | Scientific Literature | |
| 8. | ALA4406035 | F | Partial agonist activity at recombinant human A3AR expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation at 10 uM measured after 30 mins in presence of A2BAR blocker PSB-603 by Glo-sensor assay relative to Cl-IB-MECA | Homo sapiens | 3 | ALA4402597 | cell-based format | Scientific Literature | |
| 9. | ALA4406036 | F | Partial agonist activity at recombinant human A3AR expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation measured after 30 mins in presence of A2BAR blocker PSB-603 by Glo-sensor assay | Homo sapiens | 4 | ALA4402597 | cell-based format | Scientific Literature | |
| 10. | ALA4406037 | F | Antagonist activity at recombinant human A3AR expressed in HEK293 cells assessed as suppression of Cl-IB-MECA-induced inhibition of forskolin-stimulated cAMP accumulation at 10 uM measured after 30 mins in presence of A2BAR blocker PSB-603 by Glo-sensor assay | Homo sapiens | 1 | ALA4402597 | cell-based format | Scientific Literature | |
| 11. | ALA4406038 | B | Displacement of [3H]-Pentazocine from sigma 1 receptor (unknown origin) measured after 90 mins by microbeta counting analysis | Homo sapiens | 1 | ALA4402597 | single protein format | Scientific Literature | |
| 12. | ALA4406039 | B | Displacement of [3H]-DTG from sigma 2 receptor (unknown origin) measured after 90 mins by microbeta counting analysis | Homo sapiens | 1 | ALA4402597 | single protein format | Scientific Literature | |
| 13. | ALA4406040 | B | Inhibition of TSPO (unknown origin) | Homo sapiens | 3 | ALA4402597 | single protein format | Scientific Literature | |
| 14. | ALA4406041 | A | Stability in human plasma assessed as parent compound remaining measured after 120 mins | Homo sapiens | 1 | ALA4402597 | cell-free format | Scientific Literature | |
| 15. | ALA4406042 | A | Stability in rat plasma assessed as parent compound remaining measured after 120 mins | Rattus norvegicus | 1 | ALA4402597 | cell-free format | Scientific Literature | |
| 16. | ALA4406043 | A | Stability in mouse plasma assessed as parent compound remaining measured after 120 mins | Mus musculus | 1 | ALA4402597 | cell-free format | Scientific Literature | |
| 17. | ALA4406044 | A | Stability in simulated gastric fluid assessed as parent compound remaining measured after 120 mins | 1 | ALA4402597 | assay format | Scientific Literature | ||
| 18. | ALA4406045 | A | Stability in simulated intestinal fluid assessed as parent compound remaining measured after 120 mins | 1 | ALA4402597 | assay format | Scientific Literature | ||
| 19. | ALA4406046 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | ALA4402597 | single protein format | Scientific Literature | |
| 20. | ALA4406047 | A | Inhibition of CYP2C9 (unknown origin) using tolbutamide as substrate | Homo sapiens | 1 | ALA4402597 | single protein format | Scientific Literature |
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