#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4321713	Functional	Antitrypanosomal activity against Trypanosoma cruzi trypomastigotes measured after 24 hrs by resazurin dye based assay	Trypanosoma cruzi	7	ALA4316656	organism-based format	Scientific Literature
2.	ALA4321714	Functional	Antitrypanosomal activity against Trypanosoma cruzi amastigotes infected in peritoneal macrophages (unknown origin) measured after 48 hrs by resazurin dye based assay	Trypanosoma cruzi	7	ALA4316656	organism-based format	Scientific Literature
3.	ALA4321715	ADME	Cytotoxicity against mouse L929 cells measured after 48 hrs by MTT assay	Mus musculus	4	ALA4316656	cell-based format	Scientific Literature
4.	ALA4321716	Toxicity	Selectivity index, ratio of CC50 for mouse L929 cells to IC50 for Trypanosoma cruzi trypomastigotes		4	ALA4316656	assay format	Scientific Literature
5.	ALA4321717	Toxicity	Selectivity index, ratio of CC50 for mouse L929 cells to IC50 for Trypanosoma cruzi amastigotes infected in peritoneal macrophages (unknown origin)		3	ALA4316656	assay format	Scientific Literature
6.	ALA4321718	Functional	Antitrypanosomal activity against Trypanosoma cruzi amastigotes infected in peritoneal macrophages (unknown origin) assessed as elimination of parasite at 100 uM by optical microscopic analysis	Trypanosoma cruzi	2	ALA4316656	organism-based format	Scientific Literature
7.	ALA4321719	Functional	Disruption of plasma membrane integrity in Trypanosoma cruzi trypomastigotes at antitrypanosomal IC50 measured after 120 mins by Sytox green dye based fluorescence assay	Trypanosoma cruzi	2	ALA4316656	organism-based format	Scientific Literature
8.	ALA4321720	Functional	Induction of plasma membrane electric potential depolarization in Trypanosoma cruzi trypomastigotes at antitrypanosomal IC50 measured after 60 mins by DiSBAC2(3) dye based flow cytometry	Trypanosoma cruzi	2	ALA4316656	organism-based format	Scientific Literature
9.	ALA4321721	ADME	Induction of reactive oxygen species generation in Trypanosoma cruzi trypomastigotes at antitrypanosomal IC50 measured after 60 to 120 mins by H2DCFDA dye based fluorescence assay	Trypanosoma cruzi	2	ALA4316656	organism-based format	Scientific Literature
10.	ALA4321722	Functional	Induction of mitochondrial membrane potential depolarization in Trypanosoma cruzi trypomastigotes at antitrypanosomal IC50 measured after 2 hrs by JC1 dye based flow cytometry	Trypanosoma cruzi	2	ALA4316656	organism-based format	Scientific Literature
11.	ALA4321723	Functional	Induction of mitochondrial membrane potential depolarization in Trypanosoma cruzi trypomastigotes at antitrypanosomal IC50 measured after 2 hrs by DAPI/Mito tracker red dye based fluorescence microscopic analysis	Trypanosoma cruzi	2	ALA4316656	organism-based format	Scientific Literature