# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4339976 | Binding | Inhibition of FGFR1 (unknown origin) incubated for 60 mins by caliper microfluidic mobility shift technology based assay | Homo sapiens | 26 | ALA4339212 | single protein format | Scientific Literature | |
2. | ALA4339977 | Binding | Inhibition of FGFR4 (unknown origin) incubated for 60 mins by caliper microfluidic mobility shift technology based assay | Homo sapiens | 26 | ALA4339212 | single protein format | Scientific Literature | |
3. | ALA4339978 | Functional | Antiproliferative activity against human Hep3B cells with high FGFR4 expression assessed as inhibition of cell proliferation incubated for 72 hrs by CellTiter-Glo method | Homo sapiens | 26 | ALA4339212 | cell-based format | Scientific Literature | |
4. | ALA4339979 | Functional | Antiproliferative activity against human HuH7 cells with high FGFR4 expression assessed as inhibition of cell proliferation incubated for 72 hrs by CellTiter-Glo method | Homo sapiens | 26 | ALA4339212 | cell-based format | Scientific Literature | |
5. | ALA4339980 | Functional | Antiproliferative activity against human SKHEP1 cells without FGFR4 gene amplification assessed as inhibition of cell proliferation incubated for 72 hrs by CellTiter-Glo method | Homo sapiens | 26 | ALA4339212 | cell-based format | Scientific Literature | |
6. | ALA4339981 | ADME | Cmax in Sprague-Dawley rat at 5 mg/kg, ig measured after 5 mins to 24 hrs by LC-MS analysis | Rattus norvegicus | 6 | ALA4339212 | organism-based format | Scientific Literature | |
7. | ALA4339982 | ADME | AUC in Sprague-Dawley rat at 5 mg/kg, ig measured after 5 mins to 24 hrs by LC-MS analysis | Rattus norvegicus | 6 | ALA4339212 | organism-based format | Scientific Literature | |
8. | ALA4339983 | ADME | Half life in Sprague-Dawley rat at 5 mg/kg, ig measured after 5 mins to 24 hrs by LC-MS analysis | Rattus norvegicus | 6 | ALA4339212 | organism-based format | Scientific Literature | |
9. | ALA4339984 | ADME | Mean residence time in Sprague-Dawley rat at 5 mg/kg, ig measured after 5 mins to 24 hrs by LC-MS analysis | Rattus norvegicus | 6 | ALA4339212 | organism-based format | Scientific Literature |