#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4885534	Binding	Biochemical assay (BCAT1)	Homo sapiens	2	ALA4507325	single protein format	Donated Chemical Probes - SGC Frankfurt
2.	ALA4885535	Binding	Biochemical assay (BCAT2)	Homo sapiens	2	ALA4507325	single protein format	Donated Chemical Probes - SGC Frankfurt
3.	ALA4885538	Binding	Cellular mechanistic assay – BCAA measurement (U-87-MG cells)	Homo sapiens	2	ALA4507325	cell-based format	Donated Chemical Probes - SGC Frankfurt
4.	ALA5217581	Binding	Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in presence of NADH by fluorescence assay	Homo sapiens	39	ALA5214979	cell-based format	Scientific Literature
5.	ALA5217582	Binding	Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assay	Homo sapiens	27	ALA5214979	single protein format	Scientific Literature
6.	ALA5217583	ADME	Apparent permeability of the compound from apical to basolateral side in human Caco-2 cells incubated for 2 hrs by LC-MS/MS analysis	Homo sapiens	15	ALA5214979	cell-based format	Scientific Literature
7.	ALA5217584	ADME	Efflux ratio of apparent permeability in human Caco-2 cells incubated for 2 hrs by LC-MS/MS analysis	Homo sapiens	16	ALA5214979	cell-based format	Scientific Literature
8.	ALA5217585	Physicochemical	Dissociation constant, pKa of the compound		16	ALA5214979	small-molecule physicochemical format	Scientific Literature
9.	ALA5217592	ADME	Metabolic stability in human liver microsomes assessed as blood clearance incubated upto 60 mins by LC-MS/MS analysis	Homo sapiens	2	ALA5214979	microsome format	Scientific Literature
10.	ALA5217593	ADME	Metabolic stability in Wistar Han rat hepatocyte assessed as blood clearance at 1 uM incubated upto 90 mins by LC-MS/MS analysis	Rattus norvegicus	2	ALA5214979	cell-based format	Scientific Literature
11.	ALA5217594	ADME	Metabolic stability in human liver microsomes assessed as maximal oral bioavailability incubated upto 60 mins by LC-MS/MS analysis	Homo sapiens	2	ALA5214979	organism-based format	Scientific Literature
12.	ALA5217595	ADME	Metabolic stability in Wistar Han rat hepatocyte assessed as maximal oral bioavailability incubated upto 90 mins by LC-MS/MS analysis	Rattus norvegicus	2	ALA5214979	organism-based format	Scientific Literature
13.	ALA5217596	ADME	Apparent permeability of the compound from basolateral to apical side in human Caco-2 cells incubated for 2 hrs by LC-MS/MS analysis	Homo sapiens	2	ALA5214979	cell-based format	Scientific Literature
14.	ALA5217600	Functional	Upregulation of BCAA expression in human U-87 MG cells	Homo sapiens	4	ALA5214979	cell-based format	Scientific Literature
15.	ALA5217608	Physicochemical	Lipophilicity, logD of compound at pH 7.5		1	ALA5214979	small-molecule physicochemical format	Scientific Literature
16.	ALA5217609	Physicochemical	Aqueous solubility of compound in PBS buffer at pH 6.5 incubated for 24 hrs by HPLC-UV analysis		1	ALA5214979	small-molecule physicochemical format	Scientific Literature