| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA748075 | B | Displacement of [3H]glycine from NMDA receptor of rat cortical membranes | Rattus norvegicus | 15 | cell membrane format | Scientific Literature | ||
| 2. | ALA2032831 | B | Inhibition of HIV1 reverse transcriptase RNase H activity | Human immunodeficiency virus 1 | 20 | single protein format | Scientific Literature | ||
| 3. | ALA2032832 | B | Inhibition of HIV1 reverse transcriptase RNase H activity assessed as remaining activity at 100 uM | Human immunodeficiency virus 1 | 8 | single protein format | Scientific Literature | ||
| 4. | ALA2032833 | F | Antiviral activity against HIV1 infected in MT4 cells assessed as inhibition of virus-induced cytopathic effect | Human immunodeficiency virus 1 | 19 | organism-based format | Scientific Literature | ||
| 5. | ALA2032834 | A | Cytotoxicity against human MT4 cells | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 6. | ALA2032838 | B | Selectivity ratio of IC50 for HIV1 reverse transcriptase associated RNA dependent polymerase activity to IC50 for reverse transcriptase Rnase H activity | Human immunodeficiency virus 1 | 19 | single protein format | Scientific Literature | ||
| 7. | ALA2032839 | B | Selectivity ratio of IC50 for HIV1 integrase to IC50 for reverse transcriptase Rnase H activity | Human immunodeficiency virus 1 | 19 | assay format | Scientific Literature | ||
| 8. | ALA938999 | B | Inhibition of human recombinant DAAO expressed in sf9 insect cells assessed as degradation of D-serine by fluorescence assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 9. | ALA939000 | B | Inhibition of human recombinant DDO expressed in sf9 insect cells assessed as degradation of D-serine by fluorescence assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 10. | ALA939001 | B | Inhibition of rat recombinant DAAO expressed in sf9 insect cells assessed as degradation of D-serine by fluorescence assay | Rattus norvegicus | 27 | cell-based format | Scientific Literature | ||
| 11. | ALA939002 | A | Clearance in Sprague-Dawley CD rat plasma at 3 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA939003 | A | Volume of distribution in Sprague-Dawley CD rat at 3 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA939004 | A | Half life in Sprague-Dawley CD rat at 3 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA939005 | A | Oral bioavailability in Sprague-Dawley CD rat at 3 mg/kg | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA939006 | A | Cmax in Sprague-Dawley CD rat at 3 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA939007 | F | Elevation of D-serine level in sc dosed Sprague-Dawley CD rat cerebellum by LC/MS-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA939008 | F | Elevation of D-serine level in Sprague-Dawley CD rat cerebellum at 56 mg/kg, sc by LC/MS-MS analysis relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA939009 | A | Ratio of drug level in brain to plasma in Sprague-Dawley CD rat at 56 mg/kg, sc after 4 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA939010 | A | Fraction unbound in Sprague-Dawley CD rat brain at 56 mg/kg, sc after 4 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA939011 | A | Free drug level in Sprague-Dawley CD rat brain at 56 mg/kg, sc after 4 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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