# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4406751 | Binding | Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay | Homo sapiens | 25 | ALA4402613 | single protein format | Scientific Literature | |
2. | ALA4406752 | ADME | Inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay | Homo sapiens | 25 | ALA4402613 | single protein format | Scientific Literature | |
3. | ALA4406753 | Binding | Selectivity index, ratio of IC50 for inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay to IC50 for inhibition of human ALK3 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay | Homo sapiens | 20 | ALA4402613 | assay format | Scientific Literature | |
4. | ALA4406758 | Binding | Inhibition of C-terminal nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay | Homo sapiens | 21 | ALA4402613 | cell-based format | Scientific Literature | |
5. | ALA4406759 | ADME | Inhibition of ALK5 (unknown origin) expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter measured after 24 hrs by dual luciferase reporter assay | Homo sapiens | 21 | ALA4402613 | cell-based format | Scientific Literature | |
6. | ALA4406760 | Unassigned | Selectivity index, ratio of IC50 for inhibition of ALK5 (unknown origin) expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter measured after 24 hrs by dual luciferase reporter assay to IC50 for inhibition of C-terminal nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay | Homo sapiens | 18 | ALA4402613 | cell-based format | Scientific Literature |