| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4308141 | B | Inhibition of Hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qRT-PCR analysis | Mus musculus | 23 | cell-based format | Scientific Literature | ||
| 2. | ALA4388215 | A | Substrate activity at BCRP in human Caco2 cells assessed as efflux ratio by LC-MS/MS analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA4388216 | B | Inhibition of human ERG | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 4. | ALA4388217 | B | Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR method | Mus musculus | 31 | cell-based format | Scientific Literature | ||
| 5. | ALA4388218 | F | Antiproliferative activity against medulloblastoma cells derived from conditional patched knockout mouse after 48 hrs by [3H]-thymidine incorporation assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA4388219 | P | Kinetic solubility of the compound in PBS at pH 7.4 by by UPLC-MS/MS analysis | 10 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA4388220 | A | Half life in human liver microsomes at 1 uM by UPLC-MS/MS analysis | Homo sapiens | 8 | microsome format | Scientific Literature | ||
| 8. | ALA4388221 | A | Intrinsic clearance in human liver microsomes at 1 uM by UPLC-MS/MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 9. | ALA4388222 | A | Inhibition of CYP3A4 (unknown origin) using midazolam as substrate by UPLC-MS/MS analysis | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 10. | ALA4388223 | A | Permeability of the compound after 5 hrs by PAMPA | 6 | assay format | Scientific Literature | |||
| 11. | ALA4388224 | A | Substrate activity at P-glycoprotein in human Caco2 cells assessed as efflux ratio by LC-MS/MS analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA4388225 | F | Antiproliferative activity against mouse ASZ001 cells measured after 48 hrs by MTS/PMS assay | Mus musculus | 3 | cell-based format | Scientific Literature |
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