# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4391798 | A | Cytotoxicity against human WI38 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 26 | ALA4390662 | cell-based format | Scientific Literature | |
2. | ALA4391799 | F | Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 25 | ALA4390662 | cell-based format | Scientific Literature | |
3. | ALA4391800 | F | Cytotoxicity against mouse NFS60 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Mus musculus | 23 | ALA4390662 | cell-based format | Scientific Literature | |
4. | ALA4391801 | F | Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 23 | ALA4390662 | cell-based format | Scientific Literature | |
5. | ALA4391802 | F | Potency index, ratio of doxorubicin IC50 to test compound IC50 against human MCF7 cells | Homo sapiens | 5 | ALA4390662 | cell-based format | Scientific Literature | |
6. | ALA4391803 | T | Selectivity index, ratio of IC50 for human WI38 cells to IC50 for human MCF7 cells | Homo sapiens | 25 | ALA4390662 | assay format | Scientific Literature | |
7. | ALA4391804 | U | Selectivity index, ratio of IC50 for human WI38 cells to IC50 for mouse NFS60 cells | 23 | ALA4390662 | assay format | Scientific Literature | ||
8. | ALA4391805 | T | Selectivity index, ratio of IC50 for human WI38 cells to IC50 for human HepG2 cells | Homo sapiens | 23 | ALA4390662 | assay format | Scientific Literature | |
9. | ALA4391806 | F | Induction of apoptosis in human MCF7 cells assessed as induction of cell shrinkage by phase contrast inverted fluorescence microscopy | Homo sapiens | 3 | ALA4390662 | cell-based format | Scientific Literature | |
10. | ALA4391807 | F | Induction of apoptosis in mouse NFS60 cells assessed as induction of cell shrinkage by phase contrast inverted fluorescence microscopy | Mus musculus | 3 | ALA4390662 | cell-based format | Scientific Literature | |
11. | ALA4391808 | F | Induction of apoptosis in human HepG2 cells assessed as induction of cell shrinkage by phase contrast inverted fluorescence microscopy | Homo sapiens | 3 | ALA4390662 | cell-based format | Scientific Literature | |
12. | ALA4391809 | F | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.01 +/- 0.001%) | Homo sapiens | 4 | ALA4390662 | cell-based format | Scientific Literature | |
13. | ALA4391810 | F | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.47 +/- 0.01%) | Homo sapiens | 4 | ALA4390662 | cell-based format | Scientific Literature | |
14. | ALA4391811 | F | Induction of apoptosis in human MCF7 cells assessed as total apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.48 +/- 0.01%) | Homo sapiens | 4 | ALA4390662 | cell-based format | Scientific Literature | |
15. | ALA4391812 | F | Induction of apoptosis in mouse NFS60 cells assessed as early apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.02 +/- 0.01%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
16. | ALA4391813 | F | Induction of apoptosis in mouse NFS60 cells assessed as late apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.0015 +/- 0.01%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
17. | ALA4391814 | F | Induction of apoptosis in mouse NFS60 cells assessed as total apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.495 +/- 0.01%) | Mus musculus | 4 | ALA4390662 | cell-based format | Scientific Literature | |
18. | ALA4391815 | F | Induction of apoptosis in human HepG2 cells assessed as early apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.78 +/- 0.09%) | Homo sapiens | 4 | ALA4390662 | cell-based format | Scientific Literature | |
19. | ALA4391816 | F | Induction of apoptosis in human HepG2 cells assessed as late apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.1 +/- 0.001%) | Homo sapiens | 4 | ALA4390662 | cell-based format | Scientific Literature | |
20. | ALA4391817 | F | Induction of apoptosis in human HepG2 cells assessed as total apoptotic cells at IC50 incubated for 72 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.169 +/- 0.02%) | Homo sapiens | 4 | ALA4390662 | cell-based format | Scientific Literature |