# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4429876 | B | Inhibition of glycine transporter-1B in human JAR cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by [14C]glycine addition measured after 3 hrs by scintillation proximity assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA4429877 | B | Inhibition of human glycine transporter-2 expressed in HEK293 cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by [14C]glycine addition measured after 3 hrs by scintillation proximity assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
3. | ALA4429880 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining at 3 uM incubated for 15 mins by LC-MS analysis | Homo sapiens | 15 | microsome format | Scientific Literature | ||
4. | ALA4429881 | A | Metabolic stability in rat liver microsomes assessed as parent compound remaining at 3 uM incubated for 15 mins by LC-MS analysis | Rattus norvegicus | 14 | microsome format | Scientific Literature |