# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4430333 | B | Displacement of [3H]spiperone from rat D2L dopamine receptor expressed in HEK293 cell membranes after 1 hr | Rattus norvegicus | 16 | ALA4428089 | cell-based format | Scientific Literature | |
2. | ALA4430334 | B | Displacement of [3H]spiperone from rat D3 dopamine receptor expressed in HEK293 cell membranes after 1 hr | Rattus norvegicus | 16 | ALA4428089 | cell-based format | Scientific Literature | |
3. | ALA4430335 | B | Selectivity ratio of Ki for rat D2L dopamine receptor expressed in HEK293 cells to Ki for rat D3 dopamine receptor expressed in HEK293 cells | Rattus norvegicus | 16 | ALA4428089 | cell-based format | Scientific Literature | |
4. | ALA4430336 | F | Agonist activity at human D2 dopamine receptor expressed in CHO cells by [35S]GTPgammaS binding assay | Homo sapiens | 6 | ALA4428089 | cell-based format | Scientific Literature | |
5. | ALA4430337 | F | Agonist activity at human D2 dopamine receptor expressed in CHO cells by [35S]GTPgammaS binding assay relative to dopamine | Homo sapiens | 5 | ALA4428089 | cell-based format | Scientific Literature | |
6. | ALA4430338 | F | Agonist activity at human D3 dopamine receptor expressed in CHO cells by [35S]GTPgammaS binding assay | Homo sapiens | 6 | ALA4428089 | cell-based format | Scientific Literature | |
7. | ALA4430339 | F | Agonist activity at human D3 dopamine receptor expressed in CHO cells by [35S]GTPgammaS binding assay relative to dopamine | Homo sapiens | 5 | ALA4428089 | cell-based format | Scientific Literature | |
8. | ALA4430341 | F | Neuroprotective activity against 6-OHDA induce toxicity in rat PC12 cells assessed as cell viability preincubated for 24 hrs followed by 6-OHDA addition for 24 hrs by MTT assay | Rattus norvegicus | 3 | ALA4428089 | cell-based format | Scientific Literature | |
9. | ALA4430342 | F | Neuroprotective activity against 6-OHDA induce toxicity in rat PC12 cells assessed as cell viability at 30 uM preincubated for 24 hrs followed by 6-OHDA addition for 24 hrs by MTT assay | Rattus norvegicus | 3 | ALA4428089 | cell-based format | Scientific Literature | |
10. | ALA4430345 | B | Selectivity ratio of EC50 for human D2 dopamine receptor expressed in CHO cells to EC50 for human D3 dopamine receptor expressed in CHO cells | Homo sapiens | 6 | ALA4428089 | cell-based format | Scientific Literature |