# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4322409 | B | Inhibition of mouse NKX2-5 expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as protein-induced transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
2. | ALA4322414 | B | Inhibition of mouse GATA4/mouse NKX2-5 protein-protein interaction expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as transcriptional synergy at 10 uM after 24 hrs by luciferase reporter gene assay relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
3. | ALA4322416 | B | Inhibition of mouse GATA4 expressed in Chlorocebus aethiops COS1 cells harboring NP-112 reporter gene assessed as BNP promoter-driven transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
4. | ALA4322419 | B | Modulation of GATA4/NKX2-5 protein-protein interaction in neonatal Wistar rat cardiomyocytes harboring -534/+4 bp rat BNP proximal promoter assessed as reduction in BNP-promoter driven activity at 10 to 30 preincubated for 1 hr followed by hypertrophic agonist endothelin-1 and measured after 24 hrs by luminescence method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
5. | ALA4322423 | B | Modulation of GATA4/NKX2-5 protein-protein interaction in neonatal Wistar rat cardiomyocytes harboring -534/+4 bp rat BNP proximal promoter assessed as reduction in hypertrophic response at 30 preincubated for 1 hr followed by hypertrophic agonist endothelin-1 and measured after 24 hrs by luminescence method | Rattus norvegicus | 1 | cell-based format | Scientific Literature |