| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4375378 | B | Inhibition of integrin alphavbeta6 (unknown origin) by radioligand binding assay | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
| 2. | ALA4375392 | B | Inhibition of integrin alphavbeta1 (unknown origin) expressed in human A549 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amino acids) incubated for 30 mins by fluorescent probe BCECF-AM based fluorescence assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 3. | ALA4375393 | B | Inhibition of integrin alphavbeta3 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amino acids) incubated for 30 mins by fluorescent probe BCECF-AM based fluorescence assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 4. | ALA4375394 | B | Inhibition of integrin alphavbeta5 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to human vitronectin incubated for 30 mins by fluorescent probe BCECF-AM based fluorescence assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 5. | ALA4375395 | B | Inhibition of integrin alphavbeta8 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amino acids) incubated for 30 mins by fluorescent probe BCECF-AM based fluorescence assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA4375396 | B | Inhibition of integrin alphavbeta6 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amino acids) incubated for 30 mins by fluorescent probe BCECF-AM based fluorescence assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA4375403 | B | Selectivity ratio of IC50 for integrin alphavbeta1 (unknown origin) expressed in human A549 cells to IC50 for integrin alphavbeta6 (unknown origin) expressed in human K562 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4375404 | B | Selectivity ratio of IC50 for integrin alphavbeta3 (unknown origin) expressed in human K562 cells to IC50 for integrin alphavbeta6 (unknown origin) expressed in human K562 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4375405 | B | Selectivity ratio of IC50 for integrin alphavbeta5 (unknown origin) expressed in human K562 cells to IC50 for integrin alphavbeta6 (unknown origin) expressed in human K562 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4375406 | B | Selectivity ratio of IC50 for integrin alphavbeta8 (unknown origin) expressed in human K562 cells to IC50 for integrin alphavbeta6 (unknown origin) expressed in human K562 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4375407 | P | Lipophilicity, logD of the compound at pH 7.4 by chromatographic method | 10 | small-molecule physicochemical format | Scientific Literature | |||
| 12. | ALA4375408 | A | Permeability of the compound | 10 | assay format | Scientific Literature | |||
| 13. | ALA4375409 | P | Aqueous kinetic solubility of the compund by CLND method | 10 | small-molecule physicochemical format | Scientific Literature |
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