| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4385774 | B | Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay | Human gammaherpesvirus 8 | 25 | ALA4385596 | assay format | Scientific Literature | |
| 2. | ALA4385777 | B | Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay | Human gammaherpesvirus 8 | 6 | ALA4385596 | assay format | Scientific Literature | |
| 3. | ALA4385778 | B | Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay | Human gammaherpesvirus 8 | 6 | ALA4385596 | assay format | Scientific Literature | |
| 4. | ALA4385779 | B | Inhibition of 5'-Dy682-labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 500 uM preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay | Human gammaherpesvirus 8 | 6 | ALA4385596 | assay format | Scientific Literature | |
| 5. | ALA4385781 | B | Inhibition of 5'-Dy682-labelled LBS1/LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 500 uM preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay | Human gammaherpesvirus 8 | 6 | ALA4385596 | assay format | Scientific Literature | |
| 6. | ALA4385782 | B | Binding affinity to fluorescent labelled LBS2 DNA (unknown origin) by fluorescence polarization assay | Not specified | 45 | ALA4385596 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!