# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4476902 | B | Inhibition of human neurotrypsin | Homo sapiens | 142 | ALA4476865 | single protein format | Patent Bioactivity Data | |
2. | ALA4476903 | B | Inhibition of hog trypsin assessed as reduction in liberation of free para-nitroanilide using S-2222 substrate incubated for 20 to 30 mins | Sus scrofa | 1 | ALA4476865 | assay format | Patent Bioactivity Data | |
3. | ALA4476904 | B | Inhibition of human thrombin assessed as reduction in liberation of free para-nitroanilide using S-2266 substrate incubated for 20 to 30 mins | Homo sapiens | 1 | ALA4476865 | single protein format | Patent Bioactivity Data | |
4. | ALA4476905 | B | Inhibition of human plasmin assessed as reduction in liberation of free para-nitroanilide using S-2288 substrate incubated for 20 to 30 mins | Homo sapiens | 1 | ALA4476865 | single protein format | Patent Bioactivity Data | |
5. | ALA4476906 | B | Inhibition of human kallikrein assessed as reduction in liberation of free para-nitroanilide using S-2288 substrate incubated for 20 to 30 mins | Homo sapiens | 1 | ALA4476865 | single protein format | Patent Bioactivity Data | |
6. | ALA4476907 | B | Inhibition of human tPA assessed as reduction in liberation of free para-nitroanilide using S-2288 substrate incubated for 20 to 30 mins | Homo sapiens | 1 | ALA4476865 | single protein format | Patent Bioactivity Data | |
7. | ALA4476908 | B | Inhibition of human uPA assessed as reduction in liberation of free para-nitroanilide using S-2288 substrate incubated for 20 to 30 mins | Homo sapiens | 1 | ALA4476865 | single protein format | Patent Bioactivity Data | |
8. | ALA4476909 | B | Inhibition of human factor 10a assessed as reduction in liberation of free para-nitroanilide using S-2288 substrate incubated for 20 to 30 mins | Homo sapiens | 1 | ALA4476865 | single protein format | Patent Bioactivity Data | |
9. | ALA4476910 | T | Toxicity in C57/BL6 mouse assessed as weight loss dosed 3 times at 25 mg/kg, ip equivalent of active ingredient administered with 8 hrs gap between dose 1 and dose 2 and 16 hrs gap between dose 2 and dose 3 (Rvb = 5.67%) | Mus musculus | 1 | ALA4476865 | organism-based format | Patent Bioactivity Data | |
10. | ALA4476911 | F | Reduction in serum CAF levels in C57/BL6 mouse assessed as serum CAF levels dosed 3 times at 25 mg/kg, ip equivalent of active ingredient administered with 8 hrs gap between dose 1 and dose 2 and 16 hrs gap between dose 2 and dose 3 by Western blotting analysis (Rvb = 100%) | Mus musculus | 1 | ALA4476865 | organism-based format | Patent Bioactivity Data |