| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4383667 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring NF-kB activation level at 10'-12 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA4383668 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring NF-kB activation level at 10'-11 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA4383669 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring NF-kB activation level at 10'-10 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA4383670 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring NF-kB activation level at 10'-9 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA4383671 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring NF-kB activation level at 10'-8 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA4383672 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring NF-kB activation level at 10'-7 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA4383673 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring NF-kB activation level at 10'-6 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 8. | ALA4383674 | B | Activation of Luc-fused NFkB (unknown origin) expressed in non-stimulated human THP1 cells assessed as relative luminescence unit at 10'-12 M after 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 9. | ALA4383675 | B | Activation of Luc-fused NFkB (unknown origin) expressed in non-stimulated human THP1 cells assessed as relative luminescence unit at 10'-11 M after 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 10. | ALA4383676 | B | Activation of Luc-fused NFkB (unknown origin) expressed in non-stimulated human THP1 cells assessed as relative luminescence unit at 10'-10 M after 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 11. | ALA4383677 | B | Activation of Luc-fused NFkB (unknown origin) expressed in non-stimulated human THP1 cells assessed as relative luminescence unit at 10'-9 M after 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 12. | ALA4383678 | B | Activation of Luc-fused NFkB (unknown origin) expressed in non-stimulated human THP1 cells assessed as relative luminescence unit at 10'-8 M after 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 13. | ALA4383679 | B | Activation of Luc-fused NFkB (unknown origin) expressed in non-stimulated human THP1 cells assessed as relative luminescence unit at 10'-7 M after 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 14. | ALA4383680 | B | Activation of Luc-fused NFkB (unknown origin) expressed in non-stimulated human THP1 cells assessed as relative luminescence unit at 10'-6 M after 24 hrs by luciferase reporter gene assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 15. | ALA4383682 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring IL-1beta secretion at 10'-11 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by electrochemiluminescence assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 16. | ALA4383683 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring IL-1beta secretion at 10'-9 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by electrochemiluminescence assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 17. | ALA4383684 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring IL-1beta secretion at 10'-7 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by electrochemiluminescence assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 18. | ALA4383687 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring IL-6 secretion at 10'-11 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by electrochemiluminescence assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 19. | ALA4383688 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring IL-6 secretion at 10'-9 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by electrochemiluminescence assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 20. | ALA4383689 | B | Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring IL-6 secretion at 10'-7 M pretreated for 30 mins followed by LPS stimulation for 24 hrs by electrochemiluminescence assay (Rvb = 100%) | Homo sapiens | 11 | cell-based format | Scientific Literature |
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