| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4348830 | B | Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HTRF assay | Homo sapiens | 23 | ALA4346703 | cell-based format | Scientific Literature | |
| 2. | ALA4348831 | B | Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HTRF assay | Homo sapiens | 23 | ALA4346703 | cell-based format | Scientific Literature | |
| 3. | ALA4348832 | B | Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated for 20 mins followed by anti-IgM antibody stimulation and measured after 30 mins by alphascreen assay | Homo sapiens | 21 | ALA4346703 | cell-based format | Scientific Literature | |
| 4. | ALA4348833 | A | Inhibition of adenosine transporter in human HeLa cells assessed as reduction in [3H]adenosine uptake preincubated for 30 mins followed by [3H]adenosine addition and measured after 60 mins | Homo sapiens | 22 | ALA4346703 | cell-based format | Scientific Literature | |
| 5. | ALA4348836 | A | Inhibition of PDE1 (unknown origin) | Homo sapiens | 4 | ALA4346703 | protein format | Scientific Literature | |
| 6. | ALA4348837 | A | Inhibition of PDE2 (unknown origin) | Homo sapiens | 4 | ALA4346703 | single protein format | Scientific Literature | |
| 7. | ALA4348838 | A | Inhibition of PDE3 (unknown origin) | Homo sapiens | 4 | ALA4346703 | protein format | Scientific Literature | |
| 8. | ALA4348839 | A | Inhibition of PDE4 (unknown origin) | Homo sapiens | 4 | ALA4346703 | protein format | Scientific Literature | |
| 9. | ALA4348840 | A | Inhibition of PDE5 (unknown origin) | Homo sapiens | 3 | ALA4346703 | single protein format | Scientific Literature | |
| 10. | ALA4348841 | A | Inhibition of PDE6 (unknown origin) | Homo sapiens | 3 | ALA4346703 | protein format | Scientific Literature | |
| 11. | ALA4348842 | A | Inhibition of PDE7 (unknown origin) | Homo sapiens | 3 | ALA4346703 | protein format | Scientific Literature | |
| 12. | ALA4348843 | A | Inhibition of PDE8 (unknown origin) | Homo sapiens | 3 | ALA4346703 | single protein format | Scientific Literature | |
| 13. | ALA4348844 | A | Inhibition of PDE9 (unknown origin) | Homo sapiens | 3 | ALA4346703 | single protein format | Scientific Literature | |
| 14. | ALA4348845 | A | Inhibition of PDE10 (unknown origin) | Homo sapiens | 4 | ALA4346703 | single protein format | Scientific Literature | |
| 15. | ALA4348846 | A | Inhibition of PDE11 (unknown origin) | Homo sapiens | 3 | ALA4346703 | single protein format | Scientific Literature | |
| 16. | ALA4348847 | A | Plasma clearance in Wistar Han rat at 0.5 mg/kg, iv or 1 mg/kg, po | Rattus norvegicus | 4 | ALA4346703 | organism-based format | Scientific Literature | |
| 17. | ALA4348849 | A | Volume of distribution in Wistar Han rat | Rattus norvegicus | 7 | ALA4346703 | assay format | Scientific Literature | |
| 18. | ALA4348850 | A | Unbound volume of distribution in Wistar Han rat | Rattus norvegicus | 7 | ALA4346703 | assay format | Scientific Literature | |
| 19. | ALA4348851 | A | Half-life in Wistar Han rat | Rattus norvegicus | 7 | ALA4346703 | assay format | Scientific Literature | |
| 20. | ALA4348853 | A | Protein binding in Wistar Han rat plasma | Rattus norvegicus | 7 | ALA4346703 | cell-free format | Scientific Literature |
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